重症急性胰腺炎24例死亡病例分析  

Clinical analysis of 24 cases of death caused by severe acute pancrcatitis

作　　者：陈畅[1] 张文俊[1] 刘岩[1] 李兆申[1] 

机构地区：[1]上海长海医院消化科

出　　处：《中华消化杂志》2007年第6期382-384,共3页Chinese Journal of Digestion

摘　　要：目的探讨影响重症急性胰腺炎(SAP)患者的死亡因素及治疗措施。方法回顾分析1993年1月至2006年6月死亡的24例SAP住院患者的病历资料,统计病死率的变化、影响因素和治疗措施。结果SAP患者总病死率为6.65%(24/361)。多器官功能衰竭(MODS)是SAP主要的早期死亡原因,感染是中后期死亡的重要原因。有合并症的SAP患者的死亡风险大于无合并症者。结论MODS是SAP主要的早期死亡原因。早期监护和支持治疗可有效降低SAP患者的早期病死率,中晚期应予个体化综合性治疗,在非手术治疗、介入治疗、手术治疗中选择适合患者的治疗方案,并应重视合并症的治疗。Objective To investigate the factors impact on the mortality of severe acute pancreatitis（SAP）and the related treatment methods. Methods The data from 24 patients died of SAP from January 1993 to June 2006 were retrospectively analyzed. The factor that impact motality and treatment measures were also analyzed. Results The mortality of patients with SAP was 6.65%（24/361）. Multiple organ dysfunction sydrome （MODS） was the main cause of death in early stage of SAP. The infection was an important cause in later stage. The mortality was higher in SAP patients with other complications than those without. Conclusions MODS is the main cause of death in early stage. Close monitoring and supportive treatments in early stage can reduce mortality. Individualized treatments, including nonsurgical, surgical and interventional therapy should be adopted in later stage, with emphases on reducing complications.

关 键 词：重症急性胰腺炎 病死率 治疗 

分 类 号：R576[医药卫生—消化系统]