血清CA125、EMAb测定对子宫腺肌病诊断价值的临床评价  

Clinical analysis of value of serum CA125 and EMAb in diagnosis of adenomyosis

作　　者：高卉[1] 刘义明[1] 

机构地区：[1]广东医学院第二附属医院,广东湛江524003

出　　处：《中国热带医学》2007年第8期1383-1384,共2页China Tropical Medicine

摘　　要：目的探讨血清CA125及子宫内膜抗体(EMAb)测定对子宫腺肌病与子宫肌瘤鉴别诊断的价值。方法回顾性分析经病理检查证实的199例病例,分为两组:子宫腺肌病组64例,子宫肌瘤组135例,所有患者术前均行血清CA125、EMAb检测,B超检查。结果子宫腺肌病组血清CA125、EMAb检测阳性率是73.44%、51.56%;子宫肌瘤组血清CA125、EMAb检测阳性率是11.11%、11.85%;两组比较差异有统计学意义(P<0.01)。B超对子宫腺肌病诊断率是51.56%,较血清CA125、EMAb检测阳性率明显降低(P<0.05)。结论测定血清CA125、EMAb水平,对子宫腺肌病是较好的辅助诊断指标和鉴别诊断指标,B超检查对该病有一定诊断价值,两者联合检测能提高诊断的正确性。Objective To assess the value of detection of serum CA125 and EMAb in diagnosis of adenomyosis and differential diagnosis of hysteromyoma. Methods 199 cases confirmed by pathological diagnosis were divided into adenomyosis group consisted of 64cases and hysteromyoma group consisted of 135cases and analyzed retrospectively. The levels of serum CA125 and EMAb in the patients were determined and ultrasonography was conducted before operation. Results The positive rates of serum CA125 and EMAb were significantly higher in adenomyosis group than those in hysteromyoma group （73.44% vs 11.11% and 51.56 vs 11. 85% respectively; P 〈 0.01）. The rate of detecting adenomyosis by uhrasonography （51.56%） was remarkably lower than the positive rates of serum CA125 and EMAb （ P 〈0.05）. Conclusion Levels of serum CA125 and EMAb can serve as good indices in assistant diagnosis and differential diagnosis of adenomyosis. Uhrasonography plays a role in diagnosing this disease. Determination of serum CA125 and EMAb combined with uhrasonography may improve the accuracy of diagnosis.

关 键 词：CA125 EMAB 子宫腺肌病 

分 类 号：R-33[医药卫生]