脑活素治疗脑血管病疗效研究的系统评价  

A SYSTEMATI REVIEW OF CEREBROLYSIN IN THE TREATMENT OF CEREBROVASCULAR DISEASE

作　　者：胡怀富[1] 王淑康[1] 

机构地区：[1]山东大学流行病与卫生统计学研究所,山东济南250012

出　　处：《山东医学高等专科学校学报》2007年第3期219-221,共3页Journal of Shandong Medical College

摘　　要：目的评价脑活素治疗脑血管疾病的疗效。方法按照Cochrane系统评价的要求全面检索有关脑活素治疗脑血管疾病的原始文献,对符合纳入标准的文献采用Review manager 4.2软件进行Meta分析。结果共纳入文献9篇,746例患者参与meta分析。结果显示研究间具有一定的异质性(χ2=26.50,P=0.0009)。故采用随机效应模型分析,9篇文献的合并OR=2.44,95%的可信区间为(1.16,5.15);整体效果检验Z=2.35,P=0.02。结论从现有资料看,脑活素治疗脑血管病是有效的。Objective To assess the curative effects of cerebrolysin in treating cerebrovascular disease. Methods According to Cochrane Evaluation System, all the primitive literature on the use of cerebrolysin in treating cerebrovascular disease was reviewed, and meta-analyses of all necessary articles were made with Review Manger 4.2 software. Results 9 articles were included in this analysis, and meta-analyses were made among 746 cases. The test for heterogeneity showed χ^2 = 26.50, P = 0. 0009. The stochastic effect analyses showed OR = 2.44, and the confidence internal was 1.16-5.15. The total effect featured Z = 2.35, P = 0.02. Conclusion According to the present literature, cerebrolysin can produce some good effects on cerebrovascular disease.

关 键 词：脑活素 脑血管病 META分析 

分 类 号：R743[医药卫生—神经病学与精神病学]