阿尔茨海默氏病患者不同中医证型血液流变性及甲皱微循环的研究  

The Study of Hemorheology and Microcirculution on Different TCM Syndrome of Alzheimer's Disease

作　　者：黄召谊[1] 吴汉卿[1] 杨芙蓉[1] 邹欣[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院,湖北武汉430030

出　　处：《中国血液流变学杂志》2007年第2期225-226,236,共3页Chinese Journal of Hemorheology

摘　　要：目的研究阿尔茨海默氏病不同中医证型患者血液流变性及甲皱微循环的特点。方法阿尔茨海默氏病气虚证、肾虚证、血瘀证患者各30例及30例健康者,采用平行对照法,应用LBY-N6型旋转式血液粘度计检测血粘度,应用MCAS-2011型临床微循环图象分析系统检测甲皱微循环。结果阿尔茨海默氏病患者各不同证型组与正常对照组血液流变学指标及甲皱微循环主要指标有显著性差异(P<0.05),气虚证组、肾虚证组与血瘀证组血液流变学指标及甲皱微循环有显著性差异(P<0.05),而气虚证组与肾虚证组之间无显著性差异(P>0.05)。结论血粘度增高及甲皱微循环异常是患阿尔茨海默氏病危险因素之一,其指标可提供阿尔茨海默氏病的病因诊断及中医辨证参考。Objective To explore the hemorheological and microcirculatory changes on different TCM Syndrome in patients with Alzheimer＇s Disease（AD）.Methods The hemorheology and microcirculation was detected in 90 AD patients and 30 healthy controls.Results Compared with the control group,Alzheimer＇S Disease patients groups have statistical significant difference in main items ofhemorheology and microcirculation（P〈0.05）.Compared with the blood stasis group, the Qi deficiency groups and kidney deficiency group have statistical significant difference,Conclusions The patiens with AD have hemorheological changes.To test it will be helpful for diagnosising, analysising TCM Syndrome and conducting treatment.

关 键 词：阿尔茨海默氏病 血液流变性 甲皱微循环 

分 类 号：R749.16[医药卫生—神经病学与精神病学]