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作 者:刘桂花[1] 郑亚安[1] 周艳艳[1] 李翠香[1]
机构地区:[1]北京大学第三医院,北京100083
出 处:《中华医院感染学杂志》2007年第7期869-871,共3页Chinese Journal of Nosocomiology
摘 要:目的了解急诊科住院患者中临床分离细菌的特点,以及经验性应用抗菌药物与靶向性治疗的相关性。方法统计2005年全部送检标本分离细菌及药敏试验的数据,总结相应病例经验性与靶向性抗菌药物治疗的相关性。结果463例患者送检痰、静脉血、中段尿、创面脓液和穿刺液标本共1016份,培养分离病原菌312株,其中革兰阴性菌162株占52.24%、革兰阳性菌88株占28.1%、真菌61株占19.55%;全部分离菌株中耐药菌株共44株,经验性与靶向性抗菌药物治疗相关率为89.67%。结论急诊科住院患者病情危重、复杂,多系统疾病共存,其分离菌种与其他病房差异有统计学意义,经验性抗菌药物选择应结合细菌监测与药敏动态,真菌感染应引起高度重视。OBJECTIVE To study the characteristic of pathogenic bacteria isolated from patients in the emergency department and to investigate the relativity of experience and targeted antibiotic treatment. METHODS The pathogenic bacteria and drug sensitivity results of all samples in 2005 were analyzed and the relativity of experience and targeted antibiotic treatment was summarized. RESULTS Totally 1061 specimens were acquired from 463 patients including sputum, venous blood, middle urine, purulent fluid on wound surface and 312 strains pathogenic bacteria were isolated. 52. 09% of them were Gram-positive bacteria, 28. 29% were Gram-negative bacteria and 19.16 % were fungi. Of all pathogenic bacteria, there were 44 strains of drug-resistant bacteria. The relativity of experience and targeted antibiotic treatment was 89.67 %. CONCLUSIONS The patients admitted to the emergency department are in severe and complicated conditions, with multiple system diseases. The pathogenic bacteria of emergency department are different from the bacteria of other units. Antibiotic treatment by experience should combined with bacteria monitoring and drug sensitivity. Infection caused by fungi should be paid great attention.
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