前列腺素E_2在种植体周围龈沟液中的含量测定及其临床意义  

Assaying and clinical significance of Prstaglandin E_2 in gingival crevicular fluid of implant

作　　者：史久慧[1] 孙瑶[2] 朴松林[2] 张斌[3] 

机构地区：[1]哈尔滨医科大学口腔医学院口腔种植中心,教授黑龙江150001 [2]哈尔滨医科大学口腔医学院,医师黑龙江150001 [3]哈尔滨医科大学第二附属医院,教授黑龙江150086

出　　处：《口腔颌面修复学杂志》2007年第3期189-191,共3页Chinese Journal of Prosthodontics

摘　　要：目的:探讨前列腺素E2(Prstaglandin E2,PGE2)在种植体周龈沟液中的含量水平与种植牙牙周组织临床指数-菌斑指数(plaque index,PI),牙龈指数(gingival index,GI)和牙周探诊深度(probing pocket depths,PPD)之间的关系。方法:检查实验组36颗和对照组36颗种植体牙周情况,实验组为有明显炎症的种植体,牙周探诊深度均超过3mm。同时试纸收集种植体周围龈沟液,ELISA法检测其龈沟液中的PGE2含量,所得数据用t检验和Pearson相关分析进行统计学处理。结果:PGE2表达和患种植体周围炎的种植体牙周指数呈显著相关(P<0.05),且实验组和对照组的PGE2表达统计学差异明显(P<0.05)。结论:龈沟液中PGE2含量可为种植体周围炎病变的诊断提供客观参考。Objective： To investigate the relation between PGE2 in expression gingival crevicular fluid of implant and plaque index, gingival index, probing pocket depths. Methods： Peri-implant examination： 36 implants with 3ram or greater probing depths comprised the test group, and another 36 healthy ones with probing depths less than 3ram served as the control group. Implant crevicular fluid was collected with periopapers, and the PGE2 levels were evaluated using an enzyme immunoassay kit. T-test and Pearson correlation analysis were used to analyze the data. Result： In the test group, there was significant positive correlation between clinical parameters and the PGE2 levels（P〈0.05）. Significants difference was found in PGE2 level between test group and control group（P〈0.05）. Conclusion： It may be speculated that assaying PGE2 levels are useful diagnostic methods for peri-implantitis.

关 键 词：种植 种植体 种植体周围炎 龈沟液 前列腺素E2 

分 类 号：R783.6[医药卫生—口腔医学]