性别对冠状动脉支架置入术后新生内膜增生的影响  

Impact of Gender on Neointimal Hyperplasia Following Coronary Artery Stenting

作　　者：Kaneda H. Ako J. Kataoka T. P.J. Fitzgerald 黄欣 

机构地区：[1]Center for Research in Cardiovascular Interventions, Stanford University, Stanford, CA, United States Dr.

出　　处：《世界核心医学期刊文摘（心脏病学分册）》2007年第7期20-21,共2页

摘　　要：性别对裸金属支架置入术后长期预后是否有影响仍存在争论。本研究在一个大型支架置入术后患者队列中利用三维血管内超声检测性别对新生内膜增生的影响。以0．5mm为间隔手工探测整个支架置入节段的管腔和支架面积。使用Simpson方法，计算管腔容积、支架容积和新生内膜体积（支架容积减去管腔容积），并用支架长度标化。与男性相比，女性患者的年龄较大，更常伴有高脂血症或高血压，并且参考血管直径和平均支架面积较小。虽然女性患者中新生内膜增生和新生内膜厚度与男性患者相似，但是由于其支架面积较小，女性患者新生内膜增生的百分比（新生内膜面积除以支架面积）较高。Whether gender affects long-term outcomes after bare metal stent implantation remains controversial. The aim of this study was to examine the impact of gender on neointimal hyperplasia in a large cohort of patients after stent implantation using 3-dimensional intravascular ultrasound. Lumen and stent areas were manually traced at 0. 5-mm intervals throughout the stented segment. Using Simpson＇s method, lumen, stent, and neointimal（stent - lumen） volumes were calculated and standardized by stent length. Women were older, presented more often with hyperlipidemia or hypertension, and had smaller reference vessel diameter and mean stent area, compared with men.

关 键 词：新生内膜增生 冠状动脉支架 置入术后 性别 血管内超声检测 SIMPSON 内膜面积 女性患者 

分 类 号：R363[医药卫生—病理学]