离心-电导联用法快速评价O/W乳状液稳定性  

Centrifuge-Conductance Method for Quick Evaluation of O/W Emulsion Stability

作　　者：张福贵[1] 赵剑曦[1] 蒋家兴[1] 万东华[1] 

机构地区：[1]福州大学化学化工学院应用化学系,福州350002

出　　处：《应用化学》2007年第8期957-960,共4页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金(20373012);福建省教育厅科技项目(JB05022)资助项目

摘　　要：建立了乳状液在重力场和离心力场中的沉降/分层速率模型,利用离心加速乳状液的沉降/分层,根据分层后富水相的电导随离心时间的变化关系得到乳状液在离心场中的稳定时间tc,进而推算出乳状液在重力场中的稳定时间tg。这种离心-电导联用方法可快速评价O/W乳状液的稳定性。例如,以质量分数为4%Pluronic F68、1.2%卵磷脂、8%甘露醇和10%IPM配置的乳状液,在8000r/min离心下测得tc为22min,计算出tg为69d;定性分析得到离心分层常数KA=48.0%,结果表明,该配方可得到稳定的O/W乳状液。The sedimentation/demixing speed model of emulsion in gravitational field or centrifugal field was set up. The relationship between the conductivity and centrifugal time was obtained by accelerating the speed of sedimentation/demixing via centrifuging. The stable time （tc ） of emulsion in centrifugal field could be achieved and the stable time （tg） of emulsion in gravitational field could also be calculated by means of the model. The centrifuge-conductance method has been developed to quickly evaluate the stability of O/W emulsion in this paper. For instance, the tc of emulsion A composed of 4% Pluronic F68, 1.2% lecithin, 8% mannite and 10% IPM was 22 min when the centrifugal speed was 8 000 r/min. According to the model, the tg was 69 d and the Centrifugal demixing constant（KA） was 48%. These data demonstrate that a stable O/W emulsion can be formed using the above mentioned formulation.

关 键 词：离心-电导联用 乳状液 离心分层常数 稳定性 

分 类 号：O648[理学—物理化学]