咖啡酸锗对小鼠移植肉瘤S_(180)的抑制作用  

The Inhibitory Effect of Germanium Caffeic Acid on the Tumor S_(180)

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作  者:朱伟[1] 熊汉勇[1] 肖纯[1] 罗金艳[1] 

机构地区:[1]江西中医学院,2004级硕士研究生南昌330006

出  处:《实用中西医结合临床》2007年第4期82-83,共2页Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine

摘  要:目的:观察咖啡酸锗对小鼠移植性肉瘤S180的作用。方法:以咖啡酸锗高、中、低3个剂量连续给药10d,以生理盐水组为模型对照组,计算各剂量组对S180的抑制率。结果:咖啡酸锗高剂量对S180有较好的抑制率,低、中剂量也有一定的抑制作用,且给药前后小鼠体重明显增加。结论:咖啡酸锗对小鼠S180有抑制作用,且毒性很小。Objective;To observe the inhibitory effect of germanium caffeic acid on the turnou S180 Methods:The germanium caffeic acid was administered constantly for 1 0d with high,middle ,low does.Result:The group administered high does better inhibitory effect and the group with middle and low had a litter inhibitory effect,Moreover the mice's body weight increased evidencely during adminstering drug.Conclusion: The germanium caffeic acid has a strongly inhibitory effect and low toxicity.

关 键 词:咖啡酸锗 抗肿瘤 S180 抑制 

分 类 号:R730.263[医药卫生—肿瘤]

 

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