^(134)Cs 在小鼠睾丸的滞留过程及其诱发精原细胞染色体畸变  

EFFECT OF CHROMOSOME ABERRATIONS IN SPERMATOGONIA INDUCED BY 134 Cs RETENTION IN GERM CELLS

作　　者：朱寿彭[1] 夏芬[1] 杨卫东 

机构地区：[1]苏州医学院放射医学系

出　　处：《辐射防护》1997年第3期208-211,共4页Radiation Protection

基　　金：国家自然科学基金

摘　　要：本文研究了１３４Ｃｓ在小鼠睾丸内的滞留过程及其所诱发的精原细胞染色体畸变效应。在４７ｄ的观察期内，得出１３４Ｃｓ在睾丸内的滞留分数方程可拟合为Ｒ（ｔ）＝０．００４８ｅｘｐ（－０．１３８ｔ），式中Ｒ（ｔ）为滞留分数，ｔ为注入后时间（ｄ），由此可得出１３４Ｃｓ在睾丸内的半滞留期为５．０２ｄ；１３４Ｃｓ可诱发精原细胞染色体畸变，其畸变类型以染色单体型畸变为主；１３４Ｃｓ所致的精原细胞染色体畸变，在注入后第２ｄ畸变率显著增高。In this paper effect of chromosome aberrations in spermatogonia induced by 134 Cs retention in testes was studied.Our results indicated that a fitted equation to describe the retention of 134 Cs in testes was obtained as follows:R(t)=0.0048 exp (-0.138t).Where the T 1/2  in testes is 5.02 d.The results of investigating effect of chromosomal aberrations in spermatogonia induced by 134 Cs show that the chromosome aberration rates elevated with increasing dose and retention in testes of 134 Cs.Among the types of aberrations induced by 134 Cs,chromatid breakage was predo minant. (

关 键 词：铯134 精原细胞 睾丸 染色体畸变 

分 类 号：Q691.4[生物学—生物物理学]