28例脑转移瘤放射治疗疗效分析  

Anal ysis of radiotherapy effect and prognostic factors in brain metastase

作　　者：王牧民[1] 黄静[1] 娄云峰[1] 

机构地区：[1]洛阳市中心医院放疗科,河南洛阳471000

出　　处：《现代肿瘤医学》2007年第8期1080-1081,共2页Journal of Modern Oncology

摘　　要：目的:探讨脑转移瘤放疗疗效及预后因素。方法:从2000年5月～2002年5月对28例脑转移瘤进行放射治疗。采用6MV-X线,两侧平行相对野作全脑照射,(1.8～2)Gy/次,(36～40)Gy后缩野针对转移灶加量(14～20)Gy。结果:影像学有效率64.3%。中位生存期5.6个月,6个月生存率46.4%,1年生存率21.4%。结论:影响预后的因素主要有:KPS评分、脑转移数目、颅外有无转移和原发灶是否控制。Objective：To study the effect of radiotherapy and prognostic factors in metastatic brain tumor. Methods：From May 2000 to May 2002,28 cases of brain metastatic tumor received radiotherapy. In all cases ,radiotherapy was administered 5 days/week by means of 6 - MV photons from a linear accelerator. Patients received the whole brain radiation therapy （WBRT） with a dose of （36 -40）Gy followed by a local boost dose of radiation of （14 -20） Gy. Results： The response rate was 64.3%. Overall median survival time was 5.6 months. The 6 - month survival rate and one- year survival rate were 46.4% and 21.4% respectively. Conclusion： Karnofsky performance status （KPS）, number of brain metastase,primary tumor status and extracranial metastases are prognostic factors in patients with brain tumor metastases.

关 键 词：脑转移瘤 放射治疗 预后因素 

分 类 号：R739.41[医药卫生—肿瘤]