大肠癌患者血清胃泌素水平的测定  

Determination of Serum Levels of Gastrin in Patients with Colorectal Cancer

作　　者：余成仿[1] 赵继宗[1] 王吉甫[1] 

机构地区：[1]中山医科大学附属第一医院

出　　处：《实用癌症杂志》1997年第1期29-30,共2页The Practical Journal of Cancer

摘　　要：为探讨大肠癌是否与高胃泌素血症有关，作者采用放射免疫方法比较大肠癌患者与健康者血清胃泌素水平。大肠癌患者４６例，血清胃泌素水平为１０２．８±３２．７ｎｇ／Ｌ，正常对照者５１例，血清胃泌素水平为９８．８±２５．３ｎｇ／Ｌ，两者无显著性差异。大肠癌的不同病理类型、不同分化程度及不同分期，其血清胃泌素水平均无显著性差异。结果显示，高胃泌素血症与大肠癌的发生和发展无关。In order to discuss if there is any relation between colorectal cancer and hypergastrinemia, the serum levels of gastrin were tested in patients with colorectal cancer and compared with normal adults by radioimmunoassay.Forty six patients and fifty one normal adults were involved in this study.The median vaule of gastrin was 102.8±32.7 ng/L in patients and 98.8±25.3 ng/L in normal adults, respctively.The differences of serum levels of gastrin between two groups have no statistically significance.The differences of serum levels of gastrin between different histopathological classification, differentiation and Dukes stages of colorectal cancer also had no statistically significance.These results showed that there was no any relation between hypergastrinemia and colorectal cancer.

关 键 词：大肠癌 胃泌素 放射免疫测定法 

分 类 号：R735.340.4[医药卫生—肿瘤] R730.45[医药卫生—临床医学]