血液流变特性24小时变化规律与脑血栓相关性研究  

THE CHARACTCRISTICS OF 24H HEMORHEOLOGIC CHANGOS AND CEREBRAL EMBOLISM RELEVANCE

作　　者：张晓友[1] 唐卫[1] 胡泽溪[1] 杨风民[1] 陈苏过 林红 徐超龙[1] 王艳庆 潘淑华 牟晓秋[1] 

机构地区：[1]大庆油田总医院,黑龙江省大庆市163001

出　　处：《中国血液流变学杂志》1997年第1期26-29,共4页Chinese Journal of Hemorheology

摘　　要：选择 ５０—７０岁健康中老年人 ８２例和脑血栓病人 ８３例，测定 ２４小 时血液流变学指标，血压和脉搏动态变化。研究血液流变性昼夜变化规律与脑血栓 病的相关关系．结果表明；健康组血液流变学指标２４小时变化规律为，凌晨４：００ 至８：００呈高峰期，晚２０：００呈低峰期。其“高峰期”与“低峰期”对比，各项指标均 显示有显著性差异（Ｐ＜０．０１及 ０．００１）．而脑血栓病人表现为，在凌晨 ４：００的 “高峰期”血液粘度增高幅度加大，微循环滞留时间延长、血栓形成系数升高，在晚 ２０：００的“低峰期”血液粘下降幅反减小。提示脑血栓病患者除表现血液粘度昼夜 持续在较高状态外，对生物节律反应的敏感度亦比健康人降低。82 Chinese health men aged from 50 to 70 and 83 patients with cerebral em- bolism disease were selected. 24h blood rheology, blood pressure and pulse dynamic changes were measured. The relevance between the circadian changes of blood rheology and cerebral embolism was studied. The results showed that: in the healthy group,the circadian changes of blood rheology reached peak at 4. 00-8: 00 in the morning and low peak at 20: 00 in the evening. The various indexes between the peak and low peak had significant differences (P <0. 01 and 0. 001 ). In the patient group,however,the blood Viscosity Increased rapidly,mi- crocirculation prolonged and the coefficient of embolism raised at 4: 00 in the morning at the' peak period'. The blood viscosity decreased at 20: 00 in the evening at the ' low peak period',which indicates that the blood viscosity in higher and the sensitivity to biorhythm reaction lower in patients than in the healthy group.

关 键 词：血液流变学 中老年人 脑血栓 动态监测 

分 类 号：R743.32[医药卫生—神经病学与精神病学]