Octreotide 对门脉血流动力学的影响  

HEMODYNAMIC EVALUATION OF OCTREOTIDE ON PORTAL BOOD FLLOW

作　　者：占俊[1] 朱兆华[1] 文卓夫[1] 袁世珍[1] 罗葆明[1] 黎锦芳[1] 

机构地区：[1]中山医科大学孙逸仙纪念医院消化内科

出　　处：《中山医科大学学报》1997年第2期134-136,共3页Academic Journal of Sun Yat-sen University of Medical Sciences

基　　金：中山医科大学孙逸仙纪念医院科研基金

摘　　要：用彩色多普勒超声波观察静脉注射奥曲肽０．１ｍｇ对１７例门脉高压症患者和６例非门脉高压症患者门脉血流的影响。结果表明奥曲肽能显著地缩小门脉高压患者的门静脉主干内径（Ｐ＜０．００１），增加门脉平均血流速度（９０ｍｉｎ及２４ｈ，Ｐ＜０．０１；第７天，Ｐ＞０．０５），而平均血流量（Ｐ＞０．０５）及血流方向却无变化。非门脉高压症患者上述指标无统计学意义。The effect of single dose (0.1mg) of octreotide given intravenously on portal blood flow in 17 patients with portal hypertension and 6 patients without portal hypertension were monitored by colour pulsed Doppler ultrasound. The results indicated that octreotide significantly decreased the major portal diameter (P<0.001), and increased the average velocity of the portal blood flow (P<0.01 at 90min and 24 hours, P>0.05 in the 7th day), but had no effect on both the average quantity and the direction of the portal blood flow. No statistical change above parameters had been seen in the patients without protal hypertention after giving octreotide intravenously.

关 键 词：门静脉高血压 生长抑素 药理学 血液动力学 

分 类 号：R575.205[医药卫生—消化系统] R969.1[医药卫生—内科学]