中药联合化疗治疗Ⅲ～Ⅳ期非小细胞肺癌对生存质量的影响  

Evaluation on Effect of JinOingYin on Ouality of Life of Patients with Advanced Non-small Lung Cancer

作　　者：马磊[1] 吴迪[1] 陈文晟[1] 邓燕贞[1] 彭美芳[1] 李卫东[1] 

机构地区：[1]广州医学院附属肿瘤医院,广东广州510095

出　　处：《国际医药卫生导报》2007年第16期122-125,共4页International Medicine and Health Guidance News

摘　　要：目的通过中药与化疗联合和单纯化疗治疗晚期肺癌的比较，探讨化疗基础上联合中药治疗对生存质量的影响。方法60例晚期肺癌患者随机分组。单纯化疗组采用NVB 25mg／m^2，d1，d8，静脉推注，DDP80mg／m^2，d1，静脉滴注。3周为1疗程。联合治疗组在化疗基础上联合中药治疗。采用癌症治疗功能评估量表（FACT—L）评估治疗前后患者生存质量情况。结果联合治疗组和单纯化疗组有效率没有明显差异。联合治疗组在生理状况、社会和家庭状况、情感状况、功能状况、肺癌附加关注多个项目的评分中均较单纯化疗组为高（P〈0．05）。在免疫指标的测定中联合治疗组的各项指标也高于单纯化疗组（P〈0．05）。结论在化疗的同时给与中药金清饮剂可以明显地提高患者生活质量，同时改善机体免疫状态。Objective To evaluate the effect of traditional Chinese medicine JinQingYin on quality of life of patients with advanced non-small lung cancer. Methods Sixty patients with advanced NSCLC were randomly assigned into two groups. 30 patients in the combined treated group were given JQY and chemotherapy; the others in the control group were given chemotherapy only. They were observed for two courses with QOL estimated by FACT-L questionnaire. Results The clinical response rates are similar in two groups. QOL were improves respectively in the combined treated group, P〈0.05. And the immune factors were also elevated in the combined treated group, P〈0.05. Conclusion JQY may improve the QOL of advanced NSCLC patients and may improve the immunity function.

关 键 词：生活质量 非小细胞肺癌 中药 联合化疗 

分 类 号：R734[医药卫生—肿瘤]