脑梗死合并代谢综合征患者的临床特点分析  

Analysis of clinical characteristics of acute cerebral infarction complicated with metabolic syndrome

作　　者：赵文慧[1] 陈天风[1] 李淑娟[1] 

机构地区：[1]首都医科大学北京朝阳医院神经内科,北京100020

出　　处：《中华老年心脑血管病杂志》2007年第8期522-524,共3页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

摘　　要：目的探讨代谢综合征与急性脑梗死的关系。方法收集急性脑梗死患者222例,根据代谢是否异常分为代谢综合征组(132例)和非代谢综合征组(90例),分别对2组进行临床和颈部血管超声分析。结果代谢综合征组患者吸烟、饮酒比例高,脑梗死的复发率高达37.1%,而非代谢综合征组仅17.8%。代谢综合征组代谢紊乱主要表现为肥胖,血压高,高空腹血糖、高甘油三酯血症及低高密度脂蛋白胆固醇血症。代谢综合征组纤维蛋白原升高明显,且动脉粥样硬化及斑块形成比例高。结论代谢综合征通过促使动脉粥样硬化及血栓形成,导致急性脑血管意外的发生增加。Objective To explore the relationship between metabolic syndrome and acute cerebral infarction. Methods 222 patients with acute cerebral infarction were confirmed by brain CT or MRI. According to the revised ATPⅢ definition, the patients were divided into two groups： metabolic syndrome group （MS, n =132） and non-metabolic syndrome group（nMS, n =90）. Results In MS group, the rates of smoking and drinking were high and the rate of recurrence of cerebral infarction was much higher （37.1%） than that in nMS group （17.8%）. Compared with the nMS group, the BMI, FBG and TG increased while HDL-C decreased significantly in patients with MS group. Fibrinogen was also found elevated in MS group. Carotid and vertebral atherosclerosis especially plaques were detected much more in MS group than in nMS group. Conclusion MS increases incidence of atherosclerosis and plays an important role in cerebral infarction.

关 键 词：脑梗塞 代谢疾病 肥胖症 纤维蛋白原 动脉硬化 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R589[医药卫生—临床医学]