轻度认知损害患者的神经心理学特征  

Neuropsychological characteristics of individuals with mild cognitive impairment

作　　者：李涛[1] 于欣[1] 张岱[1] 王华丽[1] 石川[1] 陈玉芳[1] 赵学英[1] 付艺[1] 孙新宇[1] 

机构地区：[1]北京大学精神卫生研究所,北京100083

出　　处：《中华老年心脑血管病杂志》2007年第8期545-547,共3页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

基　　金：卫生部"十五"科技攻关项目(2003BA712A11-03)

摘　　要：目的探讨轻度认知损害(MCI)患者认知功能改变的特征。方法选择37例MCI患者为MCI组,同期选择40例年龄、性别等相匹配的志愿者为对照组,采用成套神经心理学测验评定两组被试者的认知功能。结果MCI组各项神经心理学测验成绩均较对照组差,差异有显著性意义(P<0.05)。结论MCI个体最主要的神经心理学特征为记忆障碍,涉及多种记忆类型的各项记忆加工过程,具有与早期阿尔茨海默病患者相似的特征。Objective To explore the characteristics of cognitive function changes in individuals with mild cognitive impairment （MCI）. Methods Thirty-seven individuals with MCI as MCI group and 40 volunteers as control group were recruited in the study. The age, gender and years of schooling were matched between the two groups. The cognitive function was evaluated with neuropsychological battery tests. Results Individuals of MCI group performed poorer than those of control group on most neuropsychological tests. The difference between the two groups was statistically significant（ P 〈0.05）. Conclusions Memory impairment is the primary characteristics in individuals with MCI, and involves all kinds of processes in many types of memory. Individuals with MCI have similar characteristics with early stage AD.

关 键 词：阿尔茨海默病 认知障碍 神经心理学测验 记忆障碍 

分 类 号：R749.1[医药卫生—神经病学与精神病学]