老年肺癌患者呼吸道深部真菌感染因素分析  

Discussion of dangerous factors of deep fungal infection in aged lung cancer patients

作　　者：陈正勤[1] 廖湘鲁[1] 刘利胜[1] 王绍平[2] 赵慧红[1] 王兴武[3] 

机构地区：[1]山东省肿瘤医院检验科,山东济南250117 [2]山东省肿瘤医院医务部,山东济南250117 [3]山东省肿瘤医院中心实验室,山东济南250117

出　　处：《中华肿瘤防治杂志》2007年第16期1238-1240,共3页Chinese Journal of Cancer Prevention and Treatment

摘　　要：目的:探讨老年肺癌患者呼吸道深部真菌感染的危险因素及预防措施。方法:对58例老年肺癌患者呼吸道深部真菌感染的临床资料进行回顾性分析。结果:老年肺癌患者呼吸道深部真菌感染的病原菌以白色念珠菌为主,占72.4%(42/58)。肺癌的分期晚、白细胞减少、长期应用多种抗生素、放化疗及各种侵入性诊疗等为真菌感染的危险因素。应用以氟康唑为主的综合治疗后,52例(89.7%)治愈,6例死亡。结论:老年肺癌患者呼吸道深部真菌感染有多种危险因素,应早期预防,早期诊断,确诊后及时应用高效低毒的氟康唑治疗有较好的疗效,同时应加强免疫与支持疗法。OBJECTIVE： To discuss the dangerous factors and preventive measures in aged lung cancer patients with deep fungal infection. METHODS： The clinical data from 56 aged lung cancer patients were collected and analysed retrospectirely. RESULTS：Candida albicans was the main pathogen in deep fungal infection （72. 4%, 42/58）. The dangerous factors were the stages of lung cancer, leucopenia, useness of several antibiotics, radiotherapy, chemotherapy and invasive diagnosis and therapy. Fluconazole was used to treat deep fungal infection with other measures. Among 58 cases, 52 cases were cured and 6 cases were dead. CONCLUSIONS： There are several dangerous factors in aged lung cancer patients with deep fungal infection. It should be prevented early, diagnose early and treated with fluconazole in time, while strengthening immunotherapy and support therapy.

关 键 词：肺肿瘤 老年人 念珠菌 白色 危险因素 氟康唑 

分 类 号：R734.2[医药卫生—肿瘤]