乳腺癌前哨淋巴结活检放射安全性的研究  

Research on the radiologic safety of the sentinel lymph node biosy in breast cancer

作　　者：任兆增[1] 杨耿侠[1] 王磊[1] 方永存[1] 陈鸣陆[1] 杨国仁[1] 王永胜[1] 

机构地区：[1]山东省肿瘤医院乳腺病防治中心,山东济南250117

出　　处：《中华肿瘤防治杂志》2007年第16期1241-1243,共3页Chinese Journal of Cancer Prevention and Treatment

摘　　要：目的：探讨乳腺癌前哨淋巴结活检术（SLNB）的放射安全性。方法：采用热释光剂量计（TLD）检测在SLNB过程中患者乳房注射部位、胸腺、盆腔性腺及医务人员优势手食指、胸腺、盆腔性腺接受的放射线剂量。2006年10月～2007年2月连续检测行乳腺单切＋SLNB的乳腺癌患者20例。结果：患者乳房注射部位的吸收剂量最大（4．427±0．241）mSv，显著高于胸腺及盆腔的吸收剂量，P值均为0．000。主刀医生、第一助手、器械护士各部位的核素吸收剂量差异无统计学意义（P值均〉0．05），远远低于我国卫生部确定的放射卫生防护基本标准。依据该标准，术者每年完成约800台SLNB手术在放射安全性方面是安全的。结论：核素法SLNB对患者和医务人员是安全的，不需要进行防护。OBJECTIVE： To study the radiologic safety of the sentinel lymph node biopsy （SLNB） in breast cancer. METHODS： SL- NB was detected with the combination of methylthionium and ^99m Tc-sulfur colloid. The thermoluminescent dosimeters （TLD） were used to detect radiation dose received by patients and medical stuff in 20 cases of SLNB from Oct. 2006 to Feb. 2007. The TLDs were set at the breast injection site, thoracic gland, and cavitas pelvis gonad of patients, and dominant hand forefinger, thoracic gland, and cavitas pelvis gonad of medical stuff. RESULTS： The mean radiation dose received at the breast injection site （4. 427 ± 0.241 ） mSv was significantly higher than that at the thoracic gland and cavitas pelvis gonad of the patients, P=0. 000. The mean radiation dose received at the different parts of different medical stuff had no significances （P〉0.05）, and were far lower than basic criterion of radiological health protection set by the Department of Health of China. According to this criterion, it would be safe for surgeons to perform 800 SLNBs annually. CONCLUSION： The SLNB in breast cancer is radiologically safe both for patients and medical stuff, and no radiologic protection is needed during operation.

关 键 词：乳腺肿瘤 前哨淋巴结活检 热释光剂量计 放射安全性 

分 类 号：R737.9[医药卫生—肿瘤]