揭阳地区食管鳞癌病理形态及淋巴结转移分析  

Analysis of Esophageal Squamous Carcinoma Morphology and Lymphatic Metastasis in Jieyang area

作　　者：倪仰鹏[1] 陈蔓[1] 谢丽霞[1] 许文兵[1] 

机构地区：[1]广东省揭阳市人民医院病理科,广东揭阳522000

出　　处：《河北医学》2007年第8期895-897,共3页Hebei Medicine

摘　　要：目的:分析揭阳地区食管鳞癌(ESC)病理形态特点及与淋巴结转移的关系。方法:对揭阳市人民医院1346例手术切除食管鳞癌标本行回顾性研究。结果:本地区ESC多发于中下段,以中老年为主,大部分中晚期发现,髓质及溃疡型多见,分化程度偏低,全组淋巴结转移率43.2%(581/1346);淋巴结转移率与肿瘤部位、分型、分期、分化有关(P<0.05)。结论:ESC在本地区大多发现较晚,且分化程度低、淋巴结转移率较高,早期发现是本地区一大难题,普查可在本地区进一步摧广。结合本地区上段ESC偏少情况,淋巴结多广泛转移及转移率较高等特点,三野清扫已无较大意义;对中下段ESC可行二野(胸腹二野)淋巴结清扫并配合放疗,可提高5年生存率及大幅提高患者生活质量。Objective： To analyze the morphologic characteristics and the relationship of esophageal carcinoma in Jieyang area. Method： 1346 cases resected esophageal squamous carcinoma in people＇ s hospital of Jieyang city were studied retrospectively. Result： In this area , most cases of ESC located in middle and lower portion of esophagus , mainly happened in middle and old age persons , most cases belonged to middle or late stages , medullary and ulcerative type were most common and degree of differentiation were low. The whole group lymph node metastatic rate were 43.2% （581/1346 cases ） , the lymph node metastatic rate related to location , tumor typing , staging and differentiation （ P 〈 0.05 ）. Conclusion： ESC in this area most cases belongs to late stage and low differentiation with high lymph node metastatic rate , early detection become a most difficult question , generalized early detection worth spreading in this area , combined with rare ESC in upper segment of esophagus , and characteristic if lymph node high metastatic rate the three area clean up operation become un - meaningful for middle and lower portion ESC can use double field （ thoracic and abdomen ） , radical lymph node clean up combine with radiotherapy can promote 5 years survive rate and life quality of

关 键 词：食管癌 病理形态 淋巴结 转移 

分 类 号：R735.1[医药卫生—肿瘤]