Wallenberg综合征的临床特点分析  

Wallenberg's syndrome:an analysis of clinical features

作　　者：黄海威[1] 付贤[1] 谭双全[1] 

机构地区：[1]中山大学附属第一医院神经科,广州510080

出　　处：《中华神经医学杂志》2007年第8期822-824,828,共4页Chinese Journal of Neuromedicine

摘　　要：目的探讨Wallenberg综合征(WS)的临床特点。方法对80例WS患者的临床资料进行分析研究。结果69例MRI阳性中66例患者为延髓梗塞所致,3例为延髓出血。患者多以眩晕、恶心、呕吐、吞咽困难、声嘶为主诉,急性起病并呈渐进性发展。除了典型的WS的症状外,还出现面瘫、肢体乏力(轻偏瘫)、复视、头痛、呃逆、面痛以及交叉性感觉障碍等症状和体征。头部磁共振成像(MRI)检查延髓病变阳性率为93.2%。结论延髓梗塞是WS的主要病因,但不是唯一原因。WS除了典型的症状和体征外,还具有非典型的临床特点。头部MRI的检查有助于WS的诊断。Objective To discuss the clinical features of the patients with Wallenberg＇s syndrome （WS）. Methods The clinical data of 80 cases with WS were retrospectively studied. Results WS of 66 among the 69 casee with MRI positive, were caused by medullary infarction and of the other 3 cases, by medullary hemorrhage. This disease broke out acutely and was progressive; at the first onset, vertigo, nausea, vomiting, dysphagia and cerclmus were the chief complaints of the patients. Except the classic WS symptoms, symptoms or signs like prosopoplegia, debility of unilateral limbs （hemiparesis）, diplopia, headache, hiccups, prosopodynia and contralateral sensory disturbance also occurred to patients with WS. The positive ratio for pathological changes of medulla oblongata was 93.2% by cerebral MRI scan. Conclusion Medullary infarction is a major cause of WS, but not the only one. Except the classic WS symptoms and signs, some new clinical manifestations can also be found. Cerebral MRI scan stands out more excellent in assisting the diagnosis of WS.

关 键 词：WALLENBERG综合征 延髓外侧梗塞 磁共振成像 

分 类 号：R743.3[医药卫生—神经病学与精神病学]