TCT检测及巴氏涂片细胞学检测在宫颈癌筛查中的对比研究  

The Clinical Application of Thinprep Cytology Test and TBS Cytology Subdivision in the Detection of Cervical Cancer

作　　者：焦桂青[1] 李建平[1] 

机构地区：[1]河北北方学院附属第一医院妇科,河北张家口075000

出　　处：《河北北方学院学报（医学版）》2007年第4期22-24,共3页Journal of Hebei North University:Medical Edition

基　　金：河北省科学技术研究与发展指导计划项目(编号:062761914)

摘　　要：目的:对液基薄层细胞检测系统Thinprep Cytology Test(TCT)及The Bethesda System(TBS)细胞学分类法在宫颈癌筛查中的应用价值进行综合评价。方法:采用液基薄层细胞检测系统检测宫颈细胞并进行TBS细胞学分类诊断,将诊断意义不明的不典型鳞状细胞(ASCUS)以上病变均列为阳性病例,病例均在阴道镜下行活检,将细胞学检测结果与活检结果作对比分析。结果:对223例行TCT及阴道镜下活检与组织病理学诊断:鳞状细胞癌(SCC)100%(12/12);高度病变88.23%(15/17);低度病变88.44%(38/45)。结论:TCT技术应用于宫颈细胞涂片筛查,与传统的巴氏图片相比明显提高了涂片的满意率及宫颈异常细胞检出率。TBS报告方式内容直观、易懂、具体、客观,TCT检查异常的病例配合阴道镜病理检查进行诊断,能及早发现宫颈早期病变,尽可能防治宫颈癌发生。Objective,To investigate the value of Thinprep cytology test（TCT） and Bethesda（TBS） cytology subdivision in the detection of cervical cancer. Methods： 223 cases with cervical cancer were detected by TCT and TBS. The samples of atypical squamous cell and more abnormal cell were positive, then compared with the positive results with colpo scopical biopsy examination. Results： The obtained result for 223 patients with cervical cancer was same with that of pathological examination. The result of Thinprep slides showed 100 % （12/12） squamous cell carcinoma（SCC）, 88.23% （15/17） high grade （HSIL） and 84. 44 % （38/45） low grade squamous intraepithelial lesions （LSIL）. Conclusion.. If combined with colpos copical and patho logical examination,TCT can find out the early cervical lesions as soon as possible. The TBS cytology subdivision is more detailed,simple and direct. It is key to prophylaxis and treatment of cervical cancer.

关 键 词：液基薄层细胞检测 TBS细胞学分类 宫颈癌 

分 类 号：R737.33[医药卫生—肿瘤]