不同静态电阻值对无抽搐电痉挛治疗后不良反应的影响  

A Control Study of the Influence of Data of Static Resistance Values of Pro-MECT for Side Effects after Treatment

作　　者：周小东[1] 朱宏日[1] 刘知源[1] 崔雅丽 祁革[1] 李亚强[1] 张新菊[1] 

机构地区：[1]解放军白求恩国际和平医院256临床部精神科,河北正定050800 [2]北京军区第二信息总站卫生队,石家庄050000

出　　处：《华北国防医药》2007年第4期11-13,共3页Medical Journal of Beijing Military Region

摘　　要：目的：观察治疗前不同静态电阻值对无抽搐电痉挛治疗后不良反应的影响。方法：选择住院精神障碍患者138例，随机分成三个研究组，每组46例。三组治疗前静态电阻值分别为第1组150～1000n、第2组1100～2000n、第3组2100～2900n。按常规进行无抽搐电痉挛治疗，每例均进行10次。观察治疗后30分钟～8小时内患者头痛、恶心呕吐和延迟性意识障碍发生率。同时选择40例康复期患者设为对照组进行对比观察，对照组除不给予电刺激以外，余过程同研究组。结果：治疗后研究组不良反应发生率：头痛为5．80％（80例次）、恶心呕吐2．39％（33例次）、延迟性意识障碍为0．15％（2例次）；对照组分别为1．50％（6例次）、0．75％（3例次）和0．00％（0例次）。第1组头痛发生率较第2和第3组低，差异具有显著性意义（P〈0．05），较对照组略高，但差异无显著性意义，第2和第3组问比较差异无显著性意义（P〉0，05），第2和第3组与对照组比较，差异具显著性意义（P〈0．05）。恶心呕吐和延迟性意识障碍发生率在三组问比较差异无显著性意义。第2和第3组恶心呕吐发生率与对照组比较差异具有显著性意义（P〈0．05）。结论：无抽搐电痉挛治疗前静态电阻值的大小对治疗后头痛发生率的影响较为明显，这是影响患者后续治疗依从性的关键性因素，如将静态电阻值控制在150～1000n范围内，其发生率最低，临床应予以重视。Objective：To study the influence of data of static resistance values of pro-MECT for side effects after treatment. Methods：We collected 138 inpatient cases and divided them randomly into three groups,with each group consisting of 46 patients, Static resistance values of the three study groups were 150 - 1 000Ω,1 100 -2 000 and 2 100 -2 900 Ω respectively. The occurrence rates of headache,nausea and vomiting were observed 30 minutes to 8 hours after treatment. Results：The occurrence rates of adverse reaction in 138 cases in headache were 5.80% （80 cases） ,in nausea or vomiting 2, 39% （33 cases） and in delayed consciousness disorder 0. 15% （2 cases）. The control group was 1.50% （6 cases） ,0.75% （3 cases）and 0.00% （0 case）. There were significant difference between the first group and the second or the third groups for headache only （,P 〈 0, 05 ） , but there were no significant difference for nausea or vomiting and delayed consciousness disorder in other groups and difference of headache rate between the second and third group was not significant （ P 〈 0.05） . There were significant difference of the rate of headache and nausea or vomiting between the study group and control group （P 〈 0, 05 ）. Conclusion：The headache rate of post-MECT is one of the key factors for compliance of patients after treatments, When the static resistance values is under 150 - 1 000 Ω,the occurrence rate is lowest and of clinical significance.

关 键 词：精神障碍 电惊厥疗法 电阻抗 不良反应 

分 类 号：R749.054[医药卫生—神经病学与精神病学]