血尿酸、纤维蛋白原、超敏C-反应蛋白与急性脑梗死的关系  

Plasma Uric Acid,Fibrinogen,High Sensitive C-reactive Protein and Acute Cerebral Infarction

作　　者：胡玲玲[1] 顾俊泉[1] 

机构地区：[1]江苏省无锡市第三人民医院神经内科,214041

出　　处：《中国微循环》2007年第4期259-261,共3页Journal of Chinese Microcirculation

摘　　要：目的探讨血尿酸(Uric acid,UA)、血纤维蛋白原(Fibrinogen,Fg)、超敏C反应蛋白(high sensitive C-reactive protein,hs-CRP)在急性脑梗死中的意义。方法对脑梗死患者98例及对照组68例进行血UA、Fg、hs-CRP的检测。结果急性脑梗死患者血清UA(334.81±94.54)μmol/L、Fg(3.85±1.18)g/L、hs-CRP(5.08±5.52)mg/L水平明显增高,差异有显著性意义(P<0.05);UA与神经功能缺损程度无关,Fg、hs-CRP与神经功能缺损程度有关。结论Fg、hs-CRP与缺血性脑血管病的发生和神经功能缺损程度有关,UA与缺血性脑血管病的发生有关而与神经功能缺损程度无关。Objective To discuss the significance of plasma uric acid（UA）, fibrinogen（Fg） and high sensitive C-reactive protein（hs-CRP） in patients with cerebral infarction. Methods The plasma levels of UA, Fg and hs-CRP were measured among cerebral infarction patients（ n = 98） and control group（ n = 68）. Results In patients with cerebral infarction, the plasma levels of UA, Fg and hs-CRP were （334. 81 ±94.54） μmol/ L, （3.85 ± 1.18） g/L and （5.08 ±5.52） mg/L, respectively, they were significantly higher than the control group（ P 〈 0.05） ; the plasma Fg and hs-CRP were positively related to the neurological deficit degree in cerebral infarction patients, but there was no significant correlation between UA and neurological deficit degree. Conclusion Fg and hs-CRP were related to the formation and progression of cerebral infarction, UA was related to the formation of cerebral infarction but had no effect on the progression.

关 键 词：血尿酸 纤维蛋白原 超敏C-反应蛋白 脑梗死 

分 类 号：R743[医药卫生—神经病学与精神病学]