偏头痛发作的血管发育异常及血浆生化因素分析  

Analysis on Plasma Biochemical Factors and Cerebral Vascular Dysplasia of Migraine Attack

作　　者：王晓燕[1] 何小波[2] 席刚明[1] 

机构地区：[1]郧阳医学院附属人民医院神经内科,湖北十堰442000 [2]郧阳医学院附属人民医院老年病科,湖北十堰442000

出　　处：《中国康复》2007年第4期245-246,共2页Chinese Journal of Rehabilitation

摘　　要：目的:评价鄂西北居民偏头痛的主要危险因素与偏头痛发生的关系。方法:64例偏头痛患者(头痛组)和50例正常人(正常组);采用脑血管造影(头痛组64例及正常组5例)和高效液相色谱-紫外光检测法(头痛组64例及正常组50例)了解脑血管发育情况及血浆内5-羟色胺(5-HT)的含量变化。结果:血管组患者脑血管发育变异率高于正常组,血浆5-HT含量低于正常组(P<0.05)。结论:偏头痛的发生为多因素共同作用的结果,其中脑血管发育异常是重要危险因素。Objective： To evaluate the risk factors of migraine in northwest of Hubei province. Methods： Sixty-four cases of migraine and 50 normal subjects were assigned to migraine group and control group respectively. The morphology of the whole cerebral vessels was observed by cerebral angiography and the levels of serum 5-hydroxytryptamine （5-HT） determined by high performance liquid chromatography-ultraviolet detection technique respectively. Results： In migraine group, the abnormal rate of the whole cerebral vessels was higher than in control group, while zerum 5-HT levels in migraine group was lower than in control group （P〈0.05）. Conclusion： The pathogenesis of migraine involves in multiple factors. The abnormality of cerebral vessels was an important risk factor.

关 键 词：偏头痛 易患因素 脑血管发育异常 

分 类 号：R747.2[医药卫生—神经病学与精神病学]