高强度聚焦超声治疗门静脉栓塞临床研究  

High-intensity focused ultrasound for the treatment of portal vein thrombus

作　　者：周宏平[1] 冯志洪[1] 赵峰[1] 薛青萍[1] 杨玉芝[1] 

机构地区：[1]徐州医学院第二附属医院肿瘤内科,江苏徐州221006

出　　处：《徐州医学院学报》2007年第8期550-553,共4页Acta Academiae Medicinae Xuzhou

基　　金：徐州市卫生局课题(xw2005057)

摘　　要：目的探讨高强度聚焦超声治疗门静脉栓塞的适应证及其临床价值。方法采用FEP-BY02型高强度聚焦超声治疗系统,对43例原发性肝癌合并门静脉癌栓患者以及4例非肿瘤患者门脉栓塞进行治疗。结果良性栓塞血流均再通,癌栓中70%血流明显改善,15%部分改善,15%无效。临床患者的KPS评分平均上升10分,6例腹腔积液减轻,30例肝功能得到改善。结论高强度聚焦超声可以作为门静脉栓塞的首选治疗方法。Objective To study the efficacy, safety and clinical value of high - intensity focused ultrasound （ HI- FU） for the treatment of portal vein benign thrombus and tumor thrombus. Methods The portal vein thrombi in a total of 43 patients with advanced primary liver carcinoma and a sum of 4 patients with no evidence of cancer, were treated with HIFU. Results Color flow signals showing recanalization were seen in all of the 4 patients with benign portal thrombi. But in the group of malignant thrombus, improved blood flow to certain extents was seen in 70% of the cancer patients, slight - to - moderate changes in 15% , no change at all in another 15%. The increase of KPS scores of the 43 cancer patients averaged 10 points. There was alleviation of ascites in 6 patients and improvement of liver function in 30 patients. Conclusion HIFU is the treatment of choice for both benign and malignant thrombi in the portal vein.

关 键 词：高强度聚焦超声 门静脉栓塞 治疗 

分 类 号：R735.7[医药卫生—肿瘤]