高原鼠兔红细胞2,3—二磷酸甘油酸含量的测定  

INVESTIGATION OF 2,3-DIPHOSPHOGLYCERIC ACID IN RBC OF PIKA AT ALTITUDE

作　　者：佘海茹 格日力[1] 陈秋红[1] 和伦高娃 魏春英 小林俊夫 久保惠嗣 

机构地区：[1]青海省高原医学科学研究所 [2]日本倍州大学

出　　处：《高原医学杂志》1997年第1期38-40,共3页Journal of High Altitude Medicine

摘　　要：本文采用紫外分光光度法对马多地区（4280m）民兔及Wistar大景全血及红细胞2，3—二磷酸甘油酸含量进行了规定，同时作血气分析及其他指标测定，结果发现鼠兔组全血2，3—DPG含量（2．45±0.39nmol／L）明显低于大鼠组（3．38±0．93nmol／L）（P＜0．05），红细胞2，3－DPG含量（4.85±0.54nmol／L）也明显低于大鼠组（5．83±1．23nmol／L），（P＜0．05），鼠兔组P50为3．27±0．01kPa，大鼠组P50为3．53±0.01kPa，提示鼠兔氧解离曲线左移，显示了对低氧环境的杰出适应。The contents of 2, 3-diphosphoglyceric acid (2, 3-DPG) in RBC and wh0le blood were measured in pikas and Wistar rats at Madu0 (4 280m). By ultraviolet spectrophotometry, the blood gas and other indices were done too. In results it were suggested that the 2, 3-DPG in whole blood was significantly lower in pikas (2. 45±0.39nmol/L)than that in rats (3. 38±0.93nmol/L) (P<0.05); 2, 3-DPG in RBC of pikas was 4. 85±0.54nmol/L ) that lower than in rats (5.83±1.23nmol/L) (P<0.05); and that, oxygen dissociation curve smifts to the left in pikas (P50=3.27±0. 01kPa),but in rats (P50=3. 53±0. 01kPa) to show the best adaptati0n to hypoxia in pika.

关 键 词：高原医学 二磷酸甘油酸 红细胞 

分 类 号：R188[医药卫生—流行病学]