supported by the National Natural Science Foundation of China(No.32060207,82072107);the project of Qinghai Provincial Science and Technology Department;China(No.2021-ZJ-738)。
supported by the National Natural Science Foundation of China(No.82060338);Qinghai Provincial Key Laboratory of Plateau Medical Application(Qinghai-Utah Joint Key Laboratory of Plateau Medicine)Funding Project(No.2022-KF-06);the Young Scientific Foundation of Qinghai University(No.2020-QYY-4).