抗凝血酶Ⅲ在急性脑梗死诊断及预测中的应用  

The application of anti-thrombin Ⅲ in diagnosis and forecast of acute cerebric infarction

作　　者：韩玉霞[1] 陈宝荣[1] 高寒[1] 曹蕴卿 冯天华[1] 

机构地区：[1]北京航天总医院检验科,北京100076

出　　处：《中国实用神经疾病杂志》2007年第6期30-31,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的说明抗凝血酶Ⅲ在急性脑梗死诊断及预测中的应用。方法急性脑梗死组和正常健康人组同时用发色底物法进行抗凝血酶Ⅲ检测。结果急性脑梗死组均值为83.0%,明显低于正常健康人100.3%。统计结果显示P<0.01。结论急性脑梗死患者抗凝血酶Ⅲ水平明显减低,血液处于高凝状态,应及时给予抗凝治疗;对有卒中危险因素的患者应定期进行抗凝血酶Ⅲ检测,及早发现患者的高凝状态及时治疗,以避免急性脑梗死的发生。Objective To demonstrate the application or anti-thrombin（AT -Ⅲ） in the diagnosis and forecart of acute cerebric infarction （ACI）. Methods All samples were divided into two groups：ACI group and normal control group. In two groups, AT-Ⅲ was detected simultaneously by chromogenic substrate. Results The mean value was significantly lower in ACI group （83.0%） than in normal control group（100.3%）. The statistical result showed P〈0.01 （83.0%-100. 3%, P〈0.01）. Conclusion The level of AT-Ⅲ in ACI patients＇ serum significantly decreased and the blood in the state of hypercoagulation anticoagulation treatment should be timely adopted. We should detect AT- Ⅲ periodically in patients with danger-factors of sudden death to find patients＇ state of hypercoagulation early and adopt treatment timely to avoid ACI.

关 键 词：抗凝血酶Ⅲ 急性脑梗死 预测 

分 类 号：R743.33[医药卫生—神经病学与精神病学]