不同牙周状况龈下菌斑中福赛斯坦纳菌分布  

Prevalence of Tannerella forsythensis in relation to periodontal status

作　　者：杨禾[1] 赵蕾[1] 孟姝[1] 吴亚菲[1] 付春华[2] 赵寰[1] 徐屹[1] 

机构地区：[1]四川大学华西口腔医院,四川成都610041 [2]四川大学华西口腔医学院重点实验室,四川成都610041

出　　处：《牙体牙髓牙周病学杂志》2007年第8期444-447,共4页Chinese Journal of Conservative Dentistry

基　　金："十五"国家科技攻关计划项目(2004BA720A26)

摘　　要：目的:分析牙周健康者和慢性牙周炎病人龈下菌斑中福赛斯坦纳菌的分布情况,探讨该菌与不同牙周状况的关系。方法:收集111例牙周健康者、108例慢性牙周炎病人,病变位点和健康位点共327个龈下菌斑,采用16S rRNA PCR方法检测福赛斯坦纳菌的分布。结果:牙周炎病人病变位点福赛斯坦纳菌检出率为56.5%,显著高于牙周健康者(10.8%,P<0.001)。慢性牙周炎病人健康位点福赛斯坦纳菌检出率为3.7%,显著低于病变位点(P<0.001),牙周健康者该菌的检出率比牙周炎健康位点高(P<0.05)。结论:龈下菌斑中福赛斯坦纳菌的存在与牙周炎症的发生有密切关系。AIM： To investigate the distribution of T. forsythensis in chronic periodontitis patients and healthy subjects. METHODS： 327 Subgingival plaque samples were collected from 108 chronic periodontitis patients and 111 healthy subjects. T. forsythensis was detected by 16S rRNA polymerase chain reaction. RESULTS： The prevalence of T.forsythensis was higher in the diseased sites than in the healthy subjects. The prevalence was 56.5% and 10.8% respectively （ P 〈 0.001 ）. The distribution of this bacteria in the healthy sites was 3.7%. The prevalence of T.forsythertsis in diseased sites was significant higher than the healthy sites （P 〈0.001 ）. The prevalence of T.forsythensis in the healthy subjects was higher than the healthy sites in periodontal patients （ P 〈 0.05 ）. CONCLUSION： Our results indicate a possible association between periodontal disease and the presence of T.forsythensis.

关 键 词：牙周炎 福赛斯坦纳菌 聚合酶链反应 

分 类 号：R781.4[医药卫生—口腔医学]