Assembling and releasing performance of supramolecular hydrogels formed from simple drug molecule as the hydrogelator  

作　　者：Yu Jiang Wang Liang Yan Li Ming Tang Jian Yu 

机构地区：[1]Laboratory of Advanced Materials, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China

出　　处：《Chinese Chemical Letters》2007年第8期1009-1012,共4页中国化学快报（英文版）

基　　金：financial support from the National Natural Science Foundation of China(No.20574041)is gratefully acknowledged.

摘　　要：A simple drug compound, 4-oxo-4-（2-pyridinylamino） butanoic acid （defined as AP）, was able to gel water at 4 wt% concentration under various conditions. In the superstructure, AP molecules assembled into fibrous aggregates driving by hydrogen bonds and π-π stacking interaction. The gels with different backbone structures released drug molecules in different speeds.A simple drug compound, 4-oxo-4-（2-pyridinylamino） butanoic acid （defined as AP）, was able to gel water at 4 wt% concentration under various conditions. In the superstructure, AP molecules assembled into fibrous aggregates driving by hydrogen bonds and π-π stacking interaction. The gels with different backbone structures released drug molecules in different speeds.

关 键 词：Supramolecular hydrogel HYDROGELATOR RELEASING 

分 类 号：R914[医药卫生—药物化学]