多焦视觉诱发电位用于诊断视神经病变(英文)  

Multifocal VEP in patients with optic nerve disease

作　　者：胡晓鹏[1] 黄时洲[2] 吴乐正[2] 

机构地区：[1]重庆医科大学附属第二医院眼科,中国重庆市1400010 [2]中山大学中山眼科中心,中国广东省广州市510060

出　　处：《国际眼科杂志》2007年第4期925-928,共4页International Eye Science

摘　　要：目的:探讨多焦视觉诱发电位在视神经病变诊断中的应用价值。方法:对15例视神经病变患者行常规眼科视力、裂隙灯检查、眼底检查、Goldmann眼压测定、眼底荧光血管造影、视野和mfVEP检查。对受检者双眼mfVEP检查的波形结果进行相互比较,并与视野检查结果进行相互比较及对应一致性分析。结果:在所有视神经病变眼均检测到明显的mfVEP波形改变,其与视野的改变具有对应一致性。部分视神经病变眼局部mfVEP波形改变同视野改变略有差别。结论:mfVEP在视神经病变的诊断中具有独特的优势,有望成为一种视神经病变诊断的新方法。双眼间比较有助于发现单眼局部的视神经损害。AIM：To determine whether the multifocal visual evoked potential （mfVEP） can be used as a clinical method to assess the patients with optic nerve disease. METHODS：Fifteen patients with optic nerve disease were examined in this study. All patients underwent visual acuity examination, slit-lamp inspection, ophthalmoscopy, Goldmann perimeter, fundus fluorescein angiography, visual field and mfVEP. Although these patients with unilateral optic nerve damage,data from both eyes were included in the analysis. RESULTS：In all patients the visual fields defect was demonstrated on the mfVEP and showed good correspondence in location of the scotoma. However, we also found some slight difference between visual field and mfVEP. In some locations, when the local visual fields were normal, mfVEP showed that its amplitude reduced. In reverse, when the local mfVEP seemed normal, visual field showed abnormity. CONCLUSION.Multifocal visual evoked potential could be used as a clinical diagnosis option in patients with optic nerve disease. Local monocular damage to the optic nerve can be measured by an interocular comparison of the mfVEP.

关 键 词：多焦视觉诱发电位 视神经病变 诊断 

分 类 号：R774.6[医药卫生—眼科]