评价室壁瘤患者左室整体和局部收缩与舒张功能受损情况(英文)  

Evaluation of Improvement in Left Ventricular Global and Regional Functions of Systolic and Diastolic in the Patients with Ventricular Aneurysm

作　　者：吴迪[1] 黄希正[1] 马淑平[1] 

机构地区：[1]河北省人民医院心脏诊断和治疗中心一科

出　　处：《中国医学计算机成像杂志》2007年第4期287-291,共5页Chinese Computed Medical Imaging

摘　　要：目的:利用放射性核素心室造影技术评价前壁心肌梗死后室壁瘤形成对左心室整体和局部的收缩及舒张功能的影响。材料和方法:患者分为对照组(G0)15名,单纯前壁心肌梗死组(G1)29名,前壁心肌梗死并发室壁瘤组(G2)15名。运用放射性核素心室造影检查技术测定心功能指标:①左室整体收缩功能参数:LVEF、TPE、PER、1/3EF、1/3ER。②左室整体舒张功能参数:TPF、PFR、1/3FF、1/3FR。③左室局部收缩功能参数:LVREF (6个节段)。④左室局部舒张功能参数:LVR1/3FF(6个节段)。结果:①左室整体收缩功能参数,在LVEF、PER、1/3EF、1/3ER中,G2较G1和G0有明显下降(P<0.001)。②左室整体舒张功能参数,PFR、1/3FF、1/3FR,G2比G1和G0有明显下降(P<0.001)。③左室局部收缩功能参数,LVREF在所有1-6节段G2较G1和G0有明显下降(P<0.01)。④左室舒张功能参数,LVR1/3FF在所有1-6节段G2较G1和G0有明显下降(P<0.01)。结论:左心室壁瘤的形成对左心室整体和局部的收缩和舒张功能已经构成了严重的损害。Purpose： To assess left ventricular （LV） global and regional function of systolic and diastolic in the patients with ventricular aneurysm after anterior wall myocardial infarction, we analyzed high - temporal - resolution LV global and regional time - activity curves obtained from gated radionuclide ventriculargraphy. Materials and Methods： The patients were divided into three groups, a control group（G0） of 15 normal peoples, and two groups of patients with previous anterior wall myocardial infarction, a first group（G1） of 29 patients without aneurysm, a second group（G2） of 15 patients with aneurysm. The parameters included： OLV global systolic and diastolic function parameters, QLV regional systolic and diastolic function parameters. Results： （1） LV global systolic function： the parameters of LVEF PER 1/3EF 1/3ER in G2 were reduced significantly than that in GO and GI（P 〈 0. 001）. （2）LV global diastolic function： the parameters of PFR 1/3FF 1/3FR in G2 were reduced significantly than that in GO and G1 （P 〈 0. 001） . （3）LV regional systolic function： the parameter of LVREF in G2 were reduced significantly in all LV regional 6 segments than that in GO and G1 （P 〈 0.01） . （4）LV regional distolic function： the parameter of LVR1/3FF in G2 were reduced significantly in all LV regional 6 segments than that in G0 and G1 （P 〈 0.01）. Conclusion： Forming of left ventricniar aneurysm had produced damage on left ventricular global and regional function of systolic and diastolic.

关 键 词：放射性核素心室造影 左心室心肌梗死 左心室壁瘤 左室整体和局部功能 

分 类 号：R732.1[医药卫生—肿瘤]