图形视觉诱发电位在儿童弱视诊断中的应用  

The Evaluation on the Picture Visual Evoked Potentials in Diagnosis of Children with Amblyopia

作　　者：马克明[1] 徐宝玲[1] 刘琳琳[1] 史来婷[1] 

机构地区：[1]河南省新乡市第一人民医院,河南新乡453000

出　　处：《中国现代医生》2007年第09S期4-5,20,共3页China Modern Doctor

摘　　要：目的研究P-VEP在儿童弱视诊断中的临床应用价值,以早期治疗弱视,恢复正常的双眼视觉。方法对本市幼儿园中、小班3～5岁儿童进行图形视觉诱发电位检测,对100名单眼弱视及弱视对侧健眼和100名正常儿童进行检测,并将各组测得的P-100波幅、峰潜时值平均参数进行对比、分析、统计学处理。结果弱视眼的P-100波幅明显下降,峰潜时延长(P<0.001)不同视力其P-VEP波幅下降不同,与弱视程度有密切关系,与正常儿童相比有显著性差异(P<0.001)。弱视对侧健眼的P-VEP波幅、峰潜时与正常儿童相比也有差异性(P<0.001)。结论弱视是一种视觉功能性障碍,P-VEP检测它是双眼视觉的神经功能受到损害所致,证实了弱视对侧健眼"隐性弱视"和"亚临床性弱视"的观点,因此认为P-VEP可以作为儿童弱视早期诊断中的一项客观的重要检测手段。Objective To investigate the value of P-VEP in diagnosis of children with amblyopia,and study the effect of the treatment in the early stage of visual evoked potentials. Methods 100 children with amblyopia on one eye and 100 normal children from 3- 5 years in the kindergarten in our city were checked by P-VEP. Compared the results coming from the two groups. Results P-100 amptitude showed on P-VEP coming from amslyopic group were descended significantly, so did the latency（P〈 0.001 ）, and the diffenent degree of visual acuity descended differently,compared with the normal group,it was significant（P〈 0.001 ）, so was the opposite eye of the amblyopic eye（P〈 0.001 ）. Conclusion The P-VEP and the clinical examinations of visual acuity reflect different visual information processes,and the ＂normal＂eyes of amblyopes are not norreal. The P-VEP can act as an objective and important means to test the damage of optic nerve at the early stage in children with amblyopia.

关 键 词：儿童弱视 图形视觉诱发电位 波幅 峰潜时 

分 类 号：R777.4[医药卫生—眼科]