肝豆状核变性中西医结合治疗前后脑干听觉诱发电位的对比分析  

Contrast Analysis of Brainstem Auditory Evoked Potential in Untreated and Treated Hepatolenticular Degeneration Patients with Treatment of Combining Traditional Chinese and Western Medicine

作　　者：许圣弘[1] 蔡永亮[1] 扬任民 

机构地区：[1]安徽中医学院神经学研究所

出　　处：《中国中西医结合杂志》1997年第1期17-19,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的：为探讨中西医结合疗法对肝豆状核变性脑干听觉诱发电位患者的变化的影响。方法：对６５例肝豆状核变性患者于中西医结合驱铜治疗前后实行脑子听觉诱发电位检测，结合临床症状进行分析。结果：治疗前患者脑干听觉诱发电位的潜伏期和峰间期较健康对照组明显延长，主要表现为Ⅲ、Ⅴ波潜伏期及Ⅲ－Ⅴ、Ⅰ－Ⅴ峰间期延长。患者经中西医结合驱铜治疗后，在临床症状明显改善的同时，脑子听觉诱发电位亦显示各波潜伏期和峰间期较治疗前有显著好转。男女患者治疗前的异常率分别为２１．９７％和１９．０５％，治疗后降至９．０９％和６．７５％。结论二脑干听觉诱发电位对肝豆状核变性疾病不仅有辅助诊断价值，亦有疗效判断作用。To observe the effect of combination therapy of traditional and Western medicine (TCM-WM) on brainstem auditory evoked potential(BAEP) in hepatolenticular degeneration patients. Methods: BAEP was recorded and analysed in 65 patients with hepatolenticular degeneration (HLD) before and after decoppered TCM-WM treatment Results: The peak latency (PL) and interpeak latency (IPL) of BAEP in untreated pateents were greatly increased compared with those of control group, eSPecially in the prolongations of Ⅲ ,Ⅴ, Ⅲ- Ⅴ and Ⅰ- Ⅴ. The PL and IPL improved as improvement of clinical symptoms in HLD patients treat6d with TCM-WM than that in untreated patients. The abnormal rates of men and women in BAEP were decreased from 21. 97% and 19. 05% in untreated patients to 9.09% and 6.75% in treated patients respectively. Conclusion: BAEP not only has an complementary diagnosis hot also judge the efficacy of treatment on the HLD disease.

关 键 词：脑干听觉 肝豆状核变性 中西医结合治疗 

分 类 号：R259.755[医药卫生—中西医结合] R575.505[医药卫生—中医内科学]