性宝口服液的抗疲劳功能动物实验研究  

Application of Cryobiology and Reproductive Engineering Techniques in Laboratory Animals

作　　者：王明秀[1] 王会肖[1] 于佩华 赵庆华[1] 白玉[1] 张彦廷[1] 

机构地区：[1]华北制药集团新药研究开发有限责任公司,石家庄050015

出　　处：《中国比较医学杂志》2007年第8期I0030-I0037,共8页Chinese Journal of Comparative Medicine

摘　　要：目的考察性宝口服液的缓解体力疲劳的功能。方法根据卫生部《保健食品检验与评价技术规范》2003版中缓解体力疲劳功能检验方法进行性宝口服液的动物实验,将昆明小鼠按体重随机分成对照组、性宝口服液低剂量组、中剂量组、高剂量组和男宝胶囊组,分别给予等体积蒸馏水、性宝口服液1、2、6mL/kg及男宝胶囊0.9g/kg,ig30d,测定小鼠负重游泳时间、肝糖原含量、血清尿素氮和血乳酸曲线下面积。结果性宝口服液ig30d后,对小鼠体重无明显影响,能显著延长KM小鼠负重游泳时间(p<0.05);能显著增加小鼠肝糖元含量(p<0.01);能显著降低小鼠血清尿素氮含量(p<0.05、p<0.01)。结论性宝口服液具有缓解体力疲劳的功能。Cryobiology is a jumped-up subject which investigates the influence of low temperature on organism. This extensively studied and applied technique not only promotes the progress in biology, medicine and other sciences, but also will create huge benefits for agriculture, stockbreeding, pharmacy and food manufacturing. In particular, the cryobiology has engendered far-reaching influence on environment protection, to severe endangered animal salvation and biodiversity conservation. Laboratory animals are important experimental materials for life sciences. Several scientific trends have increased the large number of mouse models and placed an intolerable load on the financial and infrastructural resources needed to maintain these models as conventional breeding colonies in recent years. The cryobiology has been applied for breeding, preservation of genetic resources, and development of new strains of laboratory animals. Anyway, the preservation of mice model will establish the furthersome condition for further studies of mammalian genetics and difficult and complicated diseases.

关 键 词：性宝口服液 抗疲劳 

分 类 号：R-33[医药卫生]