影响胃癌术后预后的多因素分析  

Multivariate prognostic analysis in gastric carcinoma patients after radical operation

作　　者：赵中伟[1] 曾菁[1] 孙举来[1] 崔杰[1] 

机构地区：[1]马鞍山市中心医院普外科,243000

出　　处：《安徽医学》2007年第6期482-484,共3页Anhui Medical Journal

摘　　要：目的研究分析胃癌患者术后预后的影响因素。方法回顾性分析1999年8月至2006年5月间我院收治的128例胃癌手术患者,采用Kaplan-Meier生存率分析法和Logrank检验进行单因素分析,Cox比例风险模型进行多因素分析。结果单因素分析表明,其预后与PTNM分期、肿瘤浸润深度、淋巴结转移情况、手术根治程度和辅助化疗均有相关性;多因素分析显示PTNM分期、肿瘤浸润深度和淋巴结转移情况是影响患者术后生存的独立因素。结论胃癌的病理特征是评价胃癌预后的重要指标,有目的控制危险因素有助提高胃癌患者术后的生存率。Objective To analyze the prognosis of gastric cancer after radical operation. Methods From August, 1999 to May, 2006, the prognosis of 128 patients with gastric cancer who had undergone gastrectomy were analyzed. The method of univariable analysis used Kaplan - Meier analysis and Log rank analysis, muhivariable analysis used Cox proportion risk model. Results Univariable analysis demonstrated that pathologic - TNM, depth of tumor invasion, lymph node metastasis, operation method and accessorial chemotherapy influenced the patients＇prognosis. However, muhivariable analysis showed that pathologic - TNM, depth of tumor invasion and lymph node metastasis were the independent risk factors of petients＇prognosis. Conclusion The clinicopathologic features of gastric cancer are important prognostic factors. Controlling these risk factors properly may improve the survival rate.

关 键 词：胃肿瘤 外科手术 预后 COX回归分析 

分 类 号：R735.2[医药卫生—肿瘤]