惊恐障碍患者血清脂质水平的初步研究  

A preliminary study of serum lipid levels in patients with panic disorder

作　　者：袁浩龙[1] 赵玉山[1] 张莉[1] 戴永干[1] 

机构地区：[1]常州市德安医院

出　　处：《临床精神医学杂志》1997年第2期78-80,共3页Journal of Clinical Psychiatry

摘　　要：采用酶法测定在性别、年龄上相匹配的３０例惊恐障碍患者、３０例抑郁症患者及３０例正常对照者的血清脂质水平。结果显示：惊恐障碍患者的血清胆固醇（Ｔｃｈ）水平明显高于抑郁症患者和正常对照者，稳定内科疾病与高血清Ｔｃｈ水平无关；在抑郁症组中，焦虑障碍史与高血清Ｔｃｈ水平明显有关。提示惊恐障碍患者的高血清Ｔｃｈ水平，可能涉及去甲肾上腺素或５羟色胺活性增高假说机制。Objective:To study serum lipid levels of patients with panic disorder.Method:Using enzymatic assay,the serum lipid levels of 30 patients with panic disorder were compared to those of 30 patients with major depression and 30 normal control subjects.The 3 groups were matched for age and sex.Results:The serum total cholesterol levels (Tch) of patients with panic disorder were significantly higher than those of patients with major depression and normal control subjects.Tch levels were not associated with the presence of stable medical conditions.In patients with major depression,a past history of anxiety disorder was significantly related to high Tch level.Discussion:High Tch levels in patients with panic disorders may be related to increased noradrenergic or serotonin activity.

关 键 词：惊恐障碍 脂质 胆固醇 血清 

分 类 号：R749.720.2[医药卫生—神经病学与精神病学]