均匀设计对眼镜蛇神经毒素与咖啡因配伍优化研究  

Study on Optimized Fromula of Caffeine and Chinse Cobraneurotoxin by Well-distribute Design

作　　者：黄铭[1] 郝永龙[1] 陈美荣[2] 俞丽霞[3] 

机构地区：[1]山东中医药大学第二附属医院,山东济南250011 [2]山东中医药大学附属医院,山东济南250011 [3]浙江中医药大学,浙江杭州310053

出　　处：《中华中医药学刊》2007年第9期1960-1961,共2页Chinese Archives of Traditional Chinese Medicine

摘　　要：采用均匀设计,研究眼镜蛇神经毒素(α-Cobrotoxin)与咖啡因的组方,寻找其最佳配伍。结果表明眼镜蛇神经毒素起主要镇痛作用,咖啡因具有协同镇痛作用,为咖啡因用于镇痛提供实验依据。To reseach the ratio of Chinese cobraneurotoxin and caffeine in optimized formula by well- distribute design. Results showed Chinese cobraneurotoxin played the main role in analgesia, caffeine had the synergistic analgesic effect . The research provided the experimental basis of caffeine applied in drug with analgesia .

关 键 词：眼镜蛇神经毒素 咖啡因 镇痛 均匀设计 

分 类 号：R285.5[医药卫生—中药学]