慢性牙周炎在急性冠脉综合征人群中的发病情况及二者关系的初步探讨  

A study of the association between chronic periodontitis and acute coronary syndrome

作　　者：关晶[1] 王胜涛[1] 杜荣品[1] 宋维来[2] 

机构地区：[1]河北省人民医院,石家庄050051 [2]卫生部北京医院

出　　处：《现代口腔医学杂志》2007年第5期514-516,共3页Journal of Modern Stomatology

基　　金：河北省科技攻关计划项目(07276101D-54)

摘　　要：目的探讨慢性牙周炎在急性冠脉综合征人群中的发病情况。方法收集60例临床上确诊为急性冠脉综合征的患者和另外60例临床证实无急性冠脉综合征的牙科查体志愿者,对其进行详尽的口腔检查。结果急性冠脉综合征患者组中重度牙周炎的发生率显著高于对照组。两组之间在一系列牙周临床特征上也存在显著差异。其中,探诊深度≥6.0mm占所探测部位的百分率在急性冠脉综合征组为14.5%,对照组为4.5%(P<0.0001);探诊出血指数,急性冠脉综合征组为28.3%,对照组为16.2%(P<0.0001);菌斑指数,急性冠脉综合征组为26%,对照组为12.5%(P<0.0001)。结论急性冠脉综合征患者人群中,中重度牙周炎的发生率显著高于对照组。本组临床数据显示,二者之间可能存在某种联系,但尚需进一步的实验研究。Objective To assess the association between chronic periodontitis （CP） and acute coronary syndrome （ACS）, Methods Sixty ACS patients and sixty healthy volunteers were enrolled in the study, Their clinical charateristics were well matched. They all received comprehensive periodontal examination, Results The occurrence of moderate and severe CP was much higher in the ACS patients as compared with the volunteers （ P 〈 0.05）. The proportion of sites with the periodontal probing depth equal or greater than 6.0mm was much higher in the ACS patients （ 14.5 % in ACS patients versus 4.5 % in volunteers, P 〈 0. 0001）. The ACS patients also had a higher bleeding score （28.30 % in ACS patients versus 16.20% in volunteers, P 〈 0.0001 ） and plaque score （26% in ACS patients versus 12.50% in volunteer, P 〈 0. 0001 ）. Conclusion ACS patients have a much higher occurrence of moderate and severe CP than volunteers. ACS was associated with a deeper periodontal probing depth and higher bleeding and plaque score.

关 键 词：慢性牙周炎 急性冠脉综舍征 牙周袋 牙菌斑指数 

分 类 号：R781.4[医药卫生—口腔医学]