原发性双侧乳腺癌诊治及预后35例分析  

An Analysis of Diagnosis, Treatment and Prognosis in 35 Cases with Bilateral Primary Breast Cancer

作　　者：尤俊[1] 许林[1] 张志明[1] 洪明[1] 

机构地区：[1]福建医科大学附属厦门第一医院,福建厦门361003

出　　处：《中国肿瘤》2007年第9期725-727,共3页China Cancer

摘　　要：[目的]探讨原发性双侧乳腺癌的诊断、治疗及影响预后的因素。[方法]1980年1月至2006年1月收治原发性双侧乳腺癌35例,均接受手术、化疗及放射治疗等综合治疗,32例获随访。[结果]全组原发性双侧乳腺癌的5、10年生存率为77.2%、55.7%;随肿瘤分期的增加,生存率降低(χ2=20.56,P<0.05);异时性双侧乳腺癌和同时性双侧乳腺癌的5年生存率分别为81.8%、58.3%(χ2=5.33,P<0.05)。[结论]原发性双侧乳腺癌的预后与临床分期有关,异时性双侧乳腺癌的预后比同时性双侧乳腺癌好。[Purpose ] To explore the diagnosis, treatment and factors influencing prognosis in bilateral primary breast cancer. [Methods] Thirty-five cases with bilateral primary breast cancer underwent surgery, chemotherapy and radiotherapy from Jan.1980 to Jan. 2006. Follow-up was available in 32 cases. [Results] In this series, 5-, 10-year survival rate of bilateral primary breast cancer was 77.2% and 55.7% respectively. The survival rate decreased with increased staging （X^2=20.56,P〈0.05）. Fiveyear survival rate of metachronous bilateral breast cancer and synchronous one was 81.8% and 58.3% （X^2=5.33 ,P〈0.05） respectively. [Conclusion] The clinical stage was an important prognostic factor for bilateral primary breast cancer. The prognosis of metachronous bilateral breast cancer was better than that of synchronous bilateral breast cancer.

关 键 词：乳腺肿瘤 诊断 治疗 预后 

分 类 号：R737.9[医药卫生—肿瘤]