桂枝二越婢一汤组合方剂解热作用的实验研究  

Experimental Studies on the Antipyretie Effect of Guizhier Yuebiyi Tang

作　　者：李静华[1] 赵秀荣[1] 郭玉成[1] 李晓军[1] 刘小刚[1] 赵玉堂[1] 

机构地区：[1]承德医学院,河北承德067000

出　　处：《时珍国医国药》2007年第9期2080-2081,共2页Lishizhen Medicine and Materia Medica Research

基　　金：国家自然科学基金项目(No.30572298)

摘　　要：目的实验研究桂枝二越婢一汤组合方剂的解热作用。方法以干酵母复制大鼠发热模型,观察桂枝汤、越婢汤及其合方桂枝二越蜱一汤的解热作用,以证实其合方中与方间存在着功效的相加、协同或拮抗关系。结果桂枝汤、越婢汤、桂枝二越蜱一汤均有解热作用(P<0.05)且桂枝二越婢一汤解热优于桂枝汤、越婢汤(P<0.05),越婢汤与桂枝汤疗效比较无意叉(P>0.05)。结论桂麻合方中方与方间有协同、拮抗关系的存在。Objective To study the antipyrectic effect of Guizhier Yuebiyi Tang. Methods Wistar rats were divided into four groups. Yeast was injected subtaneously to establish fever model. The antipyrectic effects of Guizhi Tang, Yuebi Tang, Guizhier Yuebiyi Tang were observed to confirm whether the effect of adding together, the coordination or oppressing the anti - relations exist in those herbs. Results Guizhi Tang, Yuebi Tang, and Guizhier Yuebiyi Tang had the antipyrectic effect in our study（ P 〈 0.05 ）. And Guizhier Yuebiyi Tang had better effect than the others（ P 〈 0.05 ）. There was no difference between Guizhi Tang and Yuebi Tang（ P 〉 0.05 ）. Conclusion The effect of the coordination and oppressing the anti - relations exist in these herbs.

关 键 词：桂枝汤 越婢汤 合方 解热作用 

分 类 号：R285.5[医药卫生—中药学]