影响膀胱肿瘤术后复发的 COX 回归模型多因素分析  

Recurrence of bladder tumor after surgical ablation

作　　者：魏强[1] 唐孝达[1] 杨宇如[1] 李虹[1] 张卫东[1] 陈宗福[1] 

机构地区：[1]华西医科大学附属第一医院泌尿外科

出　　处：《中华泌尿外科杂志》1997年第3期162-165,共4页Chinese Journal of Urology

摘　　要：采用ＣＯＸ回归模型对２０１例次保留膀胱手术的患者进行多因素分析，其中ＴＵＲＢｔ（经尿道膀胱肿瘤电切术）１６３例次；膀胱部分切除术３８例次，７２例次复发，总复发率３８５％。结果显示肿瘤的综合分级分期、分级、分期、既往复发史依次为影响术后肿瘤复发的主要危险因素，而术后膀胱灌注药物为主要保护性因素。同时Ｌｏｇｒａｎｋ检验计算及比较两种术式术后的复发率。结果显示Ｔ１或（和）Ｇ１患者ＴＵＲＢｔ术后的复发率低于膀胱部分切除术，Ｔ３，４或（和）Ｇ３患者膀胱部分切除术后的复发率低于ＴＵＲＢｔ，Ｔ２Ｇ２患者两种术式术后复发率无差别。cases of bladder urothelial tumor underwent surgical ablation,TUR Bt for 163 cases and partial cystectomy for 38.Tumor recurrence occured in 72 (35.8%).Cox's regression model multifactorial analysis was used to investigate the factors influencing tumor recurrence.The result revealed that the tumor grade and stage,the tumor grade,the clinical stage and the past history of recurrence were in order the factors of importance while intravesical immuno or chemotherapy being the protective factor against recurrence.With logrank test,the recurrrence rate after TUR Bt was lower than that of partial cystectomy in T 1 and/or G 1 patients while it became higher after TUR Bt than after partial cystectomy in T 3,4 and/or G 1 patients.There was no difference in recurrence rate between the two surgical procedures in T 2 G 2 patients.

关 键 词：膀胱肿瘤 癌 复发 COX模型 

分 类 号：R737.140.7[医药卫生—肿瘤] R730.7[医药卫生—临床医学]