脉络膜黑色素瘤临床病理分析  

Choroidal melanoma:clinical and histopathological study in 40 cases

作　　者：罗传淇[1] 陈荣家[1] 

机构地区：[1]上海医科大学眼耳鼻喉科医院

出　　处：《中国实用眼科杂志》1997年第4期240-242,共3页Chinese Journal of Practical Ophthalmology

摘　　要：本文总结了我院１９８５年至１９９１年经病理证实的４０例脉络膜黑色素瘤。分析其临床、超声波、眼底荧光血管造影的特点及病理改变。并对荧光血管造影的病理机制进行初步探讨。眼底荧光血管造影中于肿瘤内的低荧由肿瘤细胞及其内色素、坏死、血窦等所致。而高荧主要由肿瘤内血管和其上脱落的变性的色素上皮细胞所致。We report 40 cases of histopathologically confirmed choroidal melanoma in 21 men and 19 women ranging in age from 21 to 71 (mean 43 5)years.All cases had only uniocular lesions.Their visual acuity varied from no light perception to 25/20,with most (75%) having vision less than 20/200,depending on location of the tumor and duration of the disease.In most cases the melanoma was located posterior to the fundus,with more nasally than temporally.Five cases were complicated by secondary glaucoma,whose occurrence was associated with age,duration of the disease and size of the melanome.Hypofluorescence is always the first sign observed during fluorescein angiography,however,hyperfluorescence may be found later.The hyperfluorescence may result from vasculature in the melanoma and overlying destroyed pigment epithelial.Choroidal melanoma also shows some special signs in A ,B scan ultrasonography.At the early stage,choroidal melanoma must be differentiated from such disorders as primary retinal detachment and choroidal hemangioma,and at the last stage,from absolute primary glaucoma.

关 键 词：脉络膜黑色素瘤 眼底血管造影 病理学 

分 类 号：R739.720.2[医药卫生—肿瘤]