SCC-Ag在肺癌患者血清中表达的临床意义  

Study on the clinical significant of the SCC-Ag expression in the serum of the patient with lung cancer

作　　者：卞京文[1] 黄谦[1] 郭媛[1] 杜红梅[1] 汤艳[1] 

机构地区：[1]江苏省扬州大学医学院附属医院,225000

出　　处：《临床肺科杂志》2007年第11期1210-1211,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨肺癌患者血清中鳞状细胞癌抗原(SCC-Ag)表达的临床意义。方法用酶联免疫吸附法分析90例确诊的肺癌患者及30例肺良性疾病对照组患者血清中SCC-Ag水平,并结合临床资料分析该指标的临床意义。结果肺癌组患者血清中SCC-Ag水平明显高于肺良性疾病对照组(P<0.05);临床分期越晚,SCC-Ag水平越高,Ⅳ期患者血清中SCC-Ag水平与Ⅰ、Ⅱ、Ⅲ期患者相比有统计学差异(P<0.05);不同病理类型肺癌患者血清中SCC-Ag阳性率以鳞癌最高为68.5%。结论SCC-Ag可作为肺癌诊断、分型及判断预后的指标。Objective To investigate the clinical significant of the SCC-Ag expression in the serum of the patient with lung cancer. Methods Combining the clinical data, the level of SCC-Ag in 90 cases who wee diagnosed as lung cancer and 30 cases diagnosed as lung benign lesion （ Control Group） of elisa were analyzed. Results The level of SCC-Ag in the lung cancer was obviously higher than that in the control group. Furthermore, as the clinical stage progressed, the level of the SCC-Ag expression increased. There were significant differences in the SCC - Ag expression between Stage Ⅳ and Stage Ⅰ, and between Stage Ⅱ , and stageⅢ（ P 〈 0. 05 ）. Among the different pathological types of lung cancer, it was the SqCa that had the highest positive rate of the SCC-Ag （68.5%）. Conclusion SCC-Ag was the valuable index in diagnosing, histological typing, and prognosis assessment of lung cancer.

关 键 词：SCC—Ag 肺癌 

分 类 号：R734.2[医药卫生—肿瘤]