^(18)F-FDG PET对老年人大肠癌分期、术后再分期临床诊断的价值  

The value of ^(18)F-FDG PET in staging of colorectal cancer in elderly patients

作　　者：周润锁[1] 徐海峰[1] 孙涛[1] 袁梦晖[1] 周飞华[1] 王磊[1] 

机构地区：[1]第四军医大学唐都医院核医学科,陕西西安710038

出　　处：《现代肿瘤医学》2007年第11期1628-1630,共3页Journal of Modern Oncology

摘　　要：目的:评价18F-FDG PET对老年人大肠癌分期、术后再分期的临床价值。方法:36例经肠镜检查初步诊断为结、直肠癌的老年患者行全身18F-FDG PET检查,并在2周内完成手术及病理诊断。结果:36例病理证实为结、直肠癌,34例局部18F-FDG摄取增高,SUVmax6.931,(最大Standard Uptake Value);18F-FDGPET对肿瘤原发灶诊断准确率94.4%(34/36);局部淋巴结转移的检出率为66.7%(16/24);治疗方案改变36.1%(13/36)。随访50例老年结、直肠癌患者,26例PET阳性并证实发现局部和/或多发转移;24例PET显示阴性,其中6例随访2年后复发,阴性预测率75%。结论:18F-FDG PET显像对老年人大肠癌的分期、术后再分期诊断有较高的临床价值。To investigate the clinical value of 18^F -fluorodeoxyglucose （18^F - FDG）PET imaging in the staging and restaging diagnosis of colorectal cancer in elderly patients. Methods： A total of 36 patients with potentially aged colorectal carcinoma and other 50 patients followed up were included in this study. A whole - body FDG - PET was conducted and evaluated for increased focal uptake. Accuracy was determined by comparion of PET with surgical staging. Results： The primary tumor was visualized in 94.4% with PET. The maximum standardized uptake value（SUVmax） within the lesion were 6.9 ＋ 3.1. For simple regional lumph nodes the sensitivity was 66.7%. 36.1% of patients were facilitated in the treatment planning. In the 50 senile patients followed up, PET negative were showed in 24 and relapse in 6 cases 2 years after follow up, with an accuracy of 75%. The single and/or multiple metastases were found in 26 patients. Canclusion： FDG - PET imaging may be useful in the diagnosis and staging of colorectal carcinoma in elderly patients.

关 键 词：^18氟标记脱氧葡萄糖 正电子发射断层扫描 结肠直肠肿瘤 分期 

分 类 号：R735.3[医药卫生—肿瘤]