马达蛋白定向运动及能量转换效率的研究  

Research on Directed Motion and Energy Conversion Efficiency of Motor Proteins

作　　者：王志坚[1] 郭维生[1] 彭艳辉[2] 吉图[1] 

机构地区：[1]内蒙古大学理工学院物理系 [2]东北农业大学生物物理系,哈尔滨150030

出　　处：《现代生物医学进展》2007年第10期1458-1460,共3页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(30360028);内蒙古自治区教育厅高等学校科学研究项目(NJ03117);内蒙古自治区人才开发基金项目;内蒙古大学"513人才计划"项目资助

摘　　要：通过建立非平衡涨落下的随机跃迁的两态模型,并利用非对称的周期势和Fokker-Planck方程及其本征值法计算两态模型的几率流和稳态几率流密。结果表明马达蛋白的定向运动与有效势的整体倾斜斜率有关,定性讨论了系统能量转换效率与负载有关。Stochastically two-state hopping model in the non-equilibrium fluctuation was established. The current and effective potential in the two-state model were calculated by equation of Fokker-Planck and asymmetric periodic potential. It was shown that the directed motion of motor proteins was relevant to the slope of the effective potential. The method of eigenvalue in Fokker-Planck＇ s equation was used to calculate the probability density in stable state. The energy conversion efficiency in the system was discussed qualitatively, and the results showed that the efficiency correlates with the external load.

关 键 词：分子马达 定向运动 有效势 FOKKER-PLANCK方程 效率 

分 类 号：Q61[生物学—生物物理学]