念珠菌感染菌种的变迁及耐药现象的研究进展  

Candida species changing and drug resistance of Candida strains to antifungal agents

作　　者：陈方淳[1] 林梅[2] 

机构地区：[1]重庆医科大学附属口腔医院黏膜科,重庆400015 [2]四川大学华西口腔医院黏膜科,四川成都610041

出　　处：《国际口腔医学杂志》2007年第5期358-360,共3页International Journal of Stomatology

摘　　要：近年来,真菌感染率不断上升,念珠菌是最常见的致病菌,随着抗真菌药物的广泛应用,念珠菌有从白色念珠菌向非白色念珠菌转变的趋势,且念珠菌耐药菌株也逐年增多,所以根据体外药敏试验结果合理选择临床用药变得很有必要,但药敏试验的结果与临床疗效并非完全一致。本文就以上研究成果作一综述。Recent years, there is a rising incidence of fungal infections, and Candidas are the most common pathogen. Candidas have a tendency to change from Candida albicans to non-albicans species with the antifungal drugs used abrodly, Candida strains with drug resistance are becoming increasing prevalent yearly. So, it is very essential to rationally choose clinical drugs according to the results of antifungal susceptibility test in vitro, but the results are relative to therapeutic effect to some degree, it is not consistent completely. This is a review about some studies in this field.

关 键 词：念珠菌 菌种变迁 耐药性 

分 类 号：R780.2[医药卫生—口腔医学]