癌症患者生命质量测定量表体系之乳腺癌量表QLICP-BR的研制  

Development of the System of Quality of Life Instruments for Patients with Breast Cancer (QLICP-BR)

作　　者：杨铮[1] 汤学良[2] 万崇华[1] 邹天宁[2] 陈德颠[2] 张冬梅[3] 孟琼[1] 

机构地区：[1]昆明医学院公共卫生学院,云南昆明650031 [2]云南省肿瘤医院,云南昆明650031 [3]广东药学院管理系,广东广州510240

出　　处：《癌症》2007年第10期1122-1126,共5页Chinese Journal of Cancer

基　　金：云南省自然科学基金(No99C0016G)~~

摘　　要：背景与目的:我们已经研制了癌症患者生命质量测定量表体系的共性模块(quality of life instruments for cancer patients-general module,QLICP-GM)。本研究在此基础上再研制乳腺癌患者生命质量测定量表(QLICP-BR),并对其进行评价。方法:采用量表开发的程序化决策方式研制适合中国文化的QLICP-BR,并通过对186例乳腺癌患者进行的生存质量测定对量表进行评价。结果:总量表及各个领域的重测相关系数均在0.75以上;各领域内部一致性信度的α值除社会功能领域为0.58外,其余均在0.65以上;各条目与其领域的相关性均大于与其它领域的相关性,相关系数r值大多都在0.6以上;总量表、共性模块、躯体功能、心理功能及社会功能领域得分均显示治疗前后差异有统计学意义。结论:QLICP-BR具有较好的信度、效度和一定的反应度,可作为我国乳腺癌患者生命质量的测评工具。　BACKGROUND ＆ OBJECTIVE： The general module of the system of quality of life instruments for cancer patients, QLICP-GM, has been developed by us. Based on it, this study was to develop and evaluate the quality of life instrument for patients with breast cancer （QLICP-BR）. METHODS： Using the structured group methods of instrument development, the instrument with Chinese cultural background was developed, and evaluated by analyzing the data from 186 breast cancer patients. RESULTS： The test-retest reliability for the overall scale and 5 domains were all above 0.75. The internal consistency α for each domain was higher than 0.65 except social domain （0.58）. Most correlation coefficients between each item and the domain （that the item belongs to） were above 0.60. The differences between the scores before treatment and the scores after treatment for overall scale, general module, physical domain, psychologic domain, and social domain were significant. CONCLUSION： The QLICP-BR is of good validity, reliability and reasonable responsiveness, and can be used to assess quality of life for breast cancer patients.

关 键 词：乳腺肿瘤 生命质量 量表 评价 

分 类 号：R737.9[医药卫生—肿瘤]