实时灰阶超声造影在肝肿瘤诊断中的价值  

Diagnostic value of real-time grey-scale contrast-enhanced ultrasonography for hepatic tumors

作　　者：王洪波[1] 侯秀娟[1] 王晓蕾[1] 王虹[1] 刘爱武[1] 

机构地区：[1]哈尔滨医科大学附属第二医院超声科,黑龙江省哈尔滨市150086

出　　处：《世界华人消化杂志》2007年第25期2726-2729,共4页World Chinese Journal of Digestology

基　　金：黑龙江省教育厅基金;No.11521177~~

摘　　要：目的:评价实时灰阶超声造影在肝肿瘤诊断中的价值.方法:利用实时灰阶超声造影观察50例54个肝实质性肿块的动态增强表现作出造影诊断,并与病理对照.结果:除2例少血供胃肠道肝转移癌、1例手术后疤痕及1例炎性假瘤未见增强外,其余肿块均有不同程度的增强.肝恶性肿块早期动脉相强化,消失较快;肝血管瘤(HCH)增强速度较慢,呈周边强化;肝局灶性结节性增生(FNH)早期动脉相强化,但持续时间较长;肝硬化结节与肝实质呈同步强化.如以动脉相增强呈高回声而门脉相消失呈低回声考虑为肝恶性肿瘤,则本组超声造影诊断肝恶性肿瘤的敏感性、特异性及准确性分别为91.7%(33/36),100%(18/18)和94.4%(51/54).结论:实时灰阶超声造影可得到丰富的肝肿瘤供血及血流灌注信息,对肝肿瘤的诊断、鉴别诊断有重要的临床应用价值.AIM： To investigate the diagnostic value of new contrast agent SonoVue and real-time gray-scale contrast-enhanced ultrasonography for hepatic tumors. METHODS： We used color Doppler flow imag- ing, power Doppler imaging and real-time gray- scale contrast-enhanced ultrasonography to examine 50 patients with 54 solid hepatic lesions. All lesions were confirmed by pathology following surgery or needle biopsy. RESULTS： Fifty lesions were variously enhanced on gray-scale ultrasonography after injection of SonoVue, except for 2 cases with liver metastases, 1 of which had an operational scar and the other inflammatory pseudotumor of the liver. The sensitivity, specificity and accuracy of contrast- enhanced ultrasonography for the diagnosis of hepatic malignant tumor were 91.7% （33/36）, 100% （18/18） and 94.4% （51/54）, respectively.CONCLUSION： Real-time gray-scale contrast- enhanced ultrasonography is useful for diagnosing and discriminating hepatic tumors.

关 键 词：实时灰阶超声造影 肝肿瘤 造影剂 

分 类 号：R735.7[医药卫生—肿瘤]